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Recent Publications
Miriyala S, Spasojevic I, Tovmasyan A, Salvemini D, Vujaskovic Z, St Clair D, Batinic-Haberle I. Manganese superoxide dismutase, MnSOD and its mimics. Biochim Biophys Acta. 2011 Dec 9. [Epub ahead of print]
Janes K, Neumann WL, Salvemini D. Anti-superoxide and anti-peroxynitrite strategies in pain suppression. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(0) doi:10.1016/j.bbadis.2011.12.008
Damien S.K. Samways, Baljit S. Khakh, and Terrance M. Egan : Allosteric modulation of Ca2+ flux in a ligand-gated cation channel (P2X4) by actions on lateral portals. J. Biol. Chem. [Epub ahead of print] doi:10.1074/jbc.M111.322461.
Lavezzi HN, Parsley KP, Zahm DS (2011) Mesopontine rostromedial tegmental nucleus neurons projecting to the dorsal raphe and pedunculopontine tegmental nucleus: psychostimulant-elicited Fos expression and collateralization. Brain Struct Funct. Dec 18 [Epub ahead of print]
Srague RS, Ellsworth ML: Erythrocyte-derived ATP and perfusion distribution: Role of intracellular and intercellular communication. Microcirculation (invited manuscript) (in press).
Sridharan M, Bowles EA, Richards JP, Krantic M, Davis KL, Dietrich KA, Stephenson AH, Ellsworth ML, Sprague RS: Prostacyclin Receptor-Mediated ATP Release from Erythrocytes Requires the Voltage-Dependent Anion Channel VDAC). Am J Physiol Heart Circ Physiol. 2011 Dec 9. [Epub ahead of print].
Sprague RS, Bowles, EA, Achilleus, D., Stephenson, AH, Ellis, CG, Ellsworth, ML: A selective phosphodiesterase 3 inhibitor rescues low PO2-induced ATP release from erythrocytes of humans with type 2 diabetes: Implication for vascular control, Am. J. Physiol. Physiol. 301:H2466-72, 2011. (PMC Journal – In Process)
Thuet, KM, Bowles,EA, Sridharan, M, Adderley, SP, Ellsworth, ML, Sprague, RS, Stephenson, AH: The rho kinase inhibitor, Y27632, increases erythrocyte deformability and low oxygen tension-induced ATP release. Am. J. Physiol. (Heart and Circ). 301:H1891-6, 2011 (PMC3213963).
Rausaria S, Ghaffari MM, Kamadulski A, Rodgers K, Bryant L, Chen Z, Doyle T, Shaw MJ, Salvemini D, Neumann WL. Retooling Manganese(III) Porphyrin-Based Peroxynitrite Decomposition Catalysts for Selectivity and Oral Activity: A Potential New Strategy for Treating Chronic Pain. J Med Chem. 2011 Nov 22. [Epub ahead of print] PMID:22082008 [PubMed - as supplied by publisher]
Brasser, S.M., Silbaugh, B.C., Ketchum, M.J., Olney, J.J., and Lemon, C.H. Chemosensory responsiveness to ethanol and its individual sensory components in alcohol-preferring, -nonpreferring and genetically heterogeneous rats. Addict Biol, in press (doi:10.1111/j.1369-1600.2011.00415.x).
GLC Yosten, WK Samson. Cardiovascular Endocrinology. In: Fink G, Pfaff DW, Levine JE, eds. Handbook of Neuroendocrinology. London, Waltham, San Diego: Academic Press, Elsevier: 2012:307-328.
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Lechner, A.J., G. M. Matuschak, and D. S. Brink. (2012) Human Organ Systems: Respiratory – An Integrated Approach to Disease, New York: McGraw-Hill; 424 pp. (advance copies available October 1, 2011). Primary audience: second-year M.D. students who attend medical schools with an “organ systems” approach in their curricula (estimated by the AAMC to be at least 40% nationwide). |
Lemon C.H., Wilson D.M., Brasser S.M. Differential neural representation of oral ethanol by central taste-sensitive neurons in ethanol-preferring and genetically heterogeneous rats. J Neurophysiol; epub ahead of print September 14, 2011, doi:10.1152/jn.00580.2011
Awards and Recognitions
Dr. Daniela Salvemini has been invited to speak at the Winter Conference on Brain Research, Snowbird, Utah, USA, on January 23, 2012. The title of Dr Salvemini's lecture “Targeting Ceramide in Opiate Induced Hyperalgesia and Antinociceptive Tolerance” will be part of a workshop on “Glia: A nemesis in opioid use”.
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Gina L.C. Yosten, Ph.D., a May 2010 graduate of the doctoral program in Pharmacological and Physiological Science, and a current Postdoctoral Fellow in Dr. Samson’s laboratory in the department, has been chosen to receive the 2012 Virendra B. Mahesh Award of Excellence in Endocrinology from the America Physiological Society at the annual Experimental Biology Meeting in San Diego, California. The purpose of the Mahesh Award is to promote the career development of young investigators pursuing research in the area of Endocrinology and is presented to the graduate student or postdoctoral fellow submitting the best abstract to the Experimental Biology meeting in the area of Endocrinology and Metabolism. Dr. Yosten previously received the Research Excellence Award in 2009 and the Mead Johnson Research Recognition Award in 2011 from the Society. |
Timothy Doyle, Ph.D, post-doctoral fellow, (mentor Dr. Daniela Salvemini) was recently awarded a Future Leaders in Pain Research Grant from the American Pain Society for 2012. The grant "Sphingosine receptor 1 and morphine antinociceptive tolerance" was selected for one of three 18-month grant awards for $20,000.
Dr Daniela Salvemini was invited to give a lecture on "Novel therapeutic approaches based upon S1P targeting in pain" on September 26, 2011 in the Department of Physiology, Medical University of Innsbruck, Austria.
Drs. Bond and Griggs from the Center of World Health and Medicine (CWHM), who hold adjunct appointments in the Pharmacological and Physiological Sciences Department, have established a joint research agreement with the Institute of One World Health (iOWH) to develop new drugs to combat childhood diarrhea (http://www.slu.edu/x47844.xml). iOWH awarded the CWHM $350,000 to synthesize and evaluate the pharmacology of drug candidates.
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Thomas C. Westfall, the William Beaumont Professor and Chair, Department of Pharmacological and Physiological Science, was recently given the 2011 Distinguished Teacher Award in the category of Presentation Skills (PreClinical years) by Medical Students at Saint Louis University. |
Next page: Chairman's Letter