Saint Louis University

Faculty Biography

R. Scott Martin, PhD

Department Chair and Professor of Chemistry

Site links

Martin Group Webpage

Contact Information

229 Monsanto Hall
314-977-2836
martinrs@slu.edu

Career History

NIH Post-doctoral Fellow, Department of Pharmaceutical Chemistry, University of Kansas (1999-2002)
Assistant Professor of Chemistry, University of Iowa (2002-2003)
Assistant Professor of Chemistry, Saint Louis University, (2003-2008)
Associate Professor of Chemistry, Saint Louis University, (2008-2012)
Professor of Chemistry, Saint Louis University, (2012-Present)
Chemistry Department Chair, Saint Louis University, (2015-Present)

Education

B.S. in Chemistry, Southwest Missouri State University, cum laude, 1994
M.S. in Chemistry, Southwest Missouri State University, 1996
Ph.D. in Analytical Chemistry, The University of Missouri, Columbia, 1999

Research

Research in the Martin group has been focused on using microchip technology to study cellular systems in a manner where an analysis scheme can be integrated to study the release of neurotransmitters in close to real time.  We feel that this approach will allow us to use in vitro models to study the processes that lead to disease onset by studying cell-to-cell interaction on a molecular level and in a quantitative fashion.  This research has led us to publish many papers in this area including descriptions of advancements in microchip valving technology, the integration of electrochemical detection with microchip electrophoresis, the discovery of embedded electrodes in microchip devices for the sensitive and selective detection of nitric oxide (NO), and the development of new methods for immobilizing cells (endothelial and PC 12 cells) in microfluidic devices. In addition, we have developed methods to quantitate the amount of ATP release directly from erythrocytes when they are mechanically deformed as well as methods of rapidly measuring intracellular glutathione concentrations. We continue to work at the forefront of this exciting area, with our recent emphasis being on developing more robust cell culture on-chip to enable cell-to-cell communication studies.  Students in my group receive a broad base of training in analytical chemistry as well as biology and engineering.

Visit the Martin Research Group here.

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