Saint Louis University

Vaccine Compositions and Methods That Increase Safety of Anti-Viral Vaccination Without Loss of Efficacy

Inventor: Mark L. Buller, Ph. D.

Description:

The administration of cidofovir or analogs of cidofovir together with a smallpox vaccine, for example the Dryvax® vaccine produced by Wyeth, has been shown to cause a decrease in the side effects of vaccination without affecting the efficacy of the vaccination. The antiviral agent and the vaccine may be administered either as an admixture in a single vaccine composition or as separate compositions that are administered substantially concurrently in any order at appropriate dosage levels.

It is envisioned that the co-administration of any antiviral agent with any live vaccine will decrease the side effects of the vaccination while maintaining or improving the efficacy of the vaccine.

Application:

Vaccination against various types of viral diseases including but not limited to Smallpox virus, variola, Influenza, Mumps, Rabies, Polio, Hepatitis A, Hepatitis B, HIV, and others.

Category: Anti-viral Vaccines

Keywords: Virus treatment, combination vaccine, vaccination

Patent: U.S. Provisional 60/576,840 (filed: June 3, 2004)

License: Available

Reference Number: SLU-1023

Contact OIIP

© 1818 - 2015  SAINT LOUIS UNIVERSITY   |   Disclaimer   |  Mobile Site
St. Louis   |   Madrid