Dr. Weiss's research focuses on the use of exercise and dietary interventions to prevent and/or treat chronic disease, including diabetes, cardiovascular disease, and cancer. Secondary areas of research focus on the effects of calorie restriction on aging and on nutritional strategies to improve physical performance.
Current Research Project
Title: Calorie Restriction, Exercise, and Glucoregulation in Humans
Study Design: Randomized intervention trial
Objective: To assess the hypothesis that similar weight losses induced by caloric restriction (CR) and by exercise (EX) improve glucose tolerance and insulin action through partly distinct mechanisms and that the benefits from CR and EX are additive.
Outcomes: Glucose tolerance, insulin sensitivity, incretin hormone effect on insulin secretion, and incretin hormone response to food ingestion.
Grant/Sponsor: NIH/NIDDK, DK080886