Dale Dorsett, Ph.D.
Biochemistry and Molecular Biology
Chromosome structure control of gene expression during development using
We use Drosophila molecular genetics to understand how chromosome structure controls gene expression during development. Our studies have shed light on the molecular mechanisms of Cornelia de Lange syndrome, which causes diverse developmental deficits in humans.
Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts
from the 7th biennial scientific and educational symposium 2016
Kline AD, Krantz ID, Deardorff MA, Shirahige K, Dorsett D, Gerton JL, Wu M, Mehta D, Mills JA, Carrico CS, Noon S, Herrera PS, Horsfield JA, Bettale C, Morgan J, Huisman SA, Moss J, McCleery J, Grados M, Hansen BD, Srivastava S, Taylor-Snell E, Kerr LM, Katz O, Calof AL, Musio A, Egense A and Haaland RE
Pubmed | Am. J. Med. Genet. A
Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid
Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements
Swain A, Misulovin Z, Pherson M, Gause M, Mihindukulasuriya K, Rickels RA, Shilatifard A and Dorsett D
Pubmed | PLoS Genet.
Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular
Kreienkamp R, Croke M, Neumann MA, Bedia-Diaz G, Graziano S, Dusso A, Dorsett D, Carlberg C and Gonzalo S
Pubmed | Oncotarget