Jung Huang, Ph.D.

Professor
Biochemistry and Molecular Biology


Research

Novel trans-Golgi network signal transduction and autocrine transformation by the v-sis/c-sis oncogene, and the role of the transforming growth factor β (TGF-β) type V in the biological functions of TGF-β.

Research Interests

The areas of research in this laboratory are: 1) autocrine transformation by the v-sis/c-sis oncogene and novel trans-Golgi network (TGN) signal transduction, and 2) role of the transforming growth factor ß (TGF-ß) type V receptor (TR-V) in the biological functions of TGF-ß.

Publications

Recent

7-Dehydrocholesterol (7-DHC), But Not Cholesterol, Causes Suppression of Canonical TGF-β Signaling and Is Likely Involved in the Development of Atherosclerotic Cardiovascular Disease (ASCVD)
Huang SS, Liu IH, Chen CL, Chang JM, Johnson FE and Huang JS
Abstract
Pubmed | J. Cell. Biochem.

DMSO Enhances TGF-β Activity by Recruiting the Type II TGF-β Receptor From Intracellular Vesicles to the Plasma Membrane
Huang SS, Chen CL, Huang FW, Hou WH and Huang JS
Abstract
Pubmed | J. Cell. Biochem.

Ethanol Enhances TGF-β Activity by Recruiting TGF-β Receptors From Intracellular Vesicles/Lipid Rafts/Caveolae to Non-Lipid Raft Microdomains
Huang SS, Chen CL, Huang FW, Johnson FE and Huang JS
Abstract
Pubmed | J. Cell. Biochem.

CRSBP-1/LYVE-1 ligands stimulate contraction of the CRSBP-1-associated ER network in lymphatic endothelial cells
Hou WH, Liua IH, Huang SS and Huang JS
Abstract
Pubmed | FEBS Lett.

A mechanism by which dietary trans fats cause atherosclerosis
Chen CL, Tetri LH, Neuschwander-Tetri BA, Huang SS and Huang JS
Abstract
Pubmed | J. Nutr. Biochem.