Oleg Kisselev, Ph.D.

Associate Professor
Opthamology


Research

Studies on the mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messangers.

Research Interests

We are interested in the universal mechanism of transmembrane signal transduction mediated by heterotrimeric G-proteins, which are responsible for the transmission of information about extracellular messengers such as hormones, neurotransmitters and sensory stimuli, including visual signals.

Publications

Recent

Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex
Lomonosova E, Kolesnikov AV, Kefalov VJ and Kisselev OG
Abstract
Pubmed | Invest. Ophthalmol. Vis. Sci.

G-protein alpha and beta-gamma subunits interact with conformationally distinct signaling states of rhodopsin
Downs MA, Arimoto R, Marshall GR and Kisselev OG
Abstract
Pubmed | Vision Res.

Rhodopsin-interacting surface of the transducin gamma subunit
Kisselev OG and Downs MA
Abstract
Pubmed | Biochemistry

Focus on molecules: rhodopsin
Kisselev OG
Abstract
Pubmed | Exp. Eye Res.

The arrestin-bound conformation and dynamics of the phosphorylated carboxy-terminal region of rhodopsin
Kisselev OG, McDowell JH and Hargrave PA
Abstract
Pubmed | FEBS Lett.