The Saint Louis University Institute for Molecular Virology was established in 1964 to provide a unique faculty and special facilities for research and teaching in molecular virology, viral oncology and cancer biology.
The institute's research programs use DNA tumor viruses and retroviruses as models to understand the molecular basis of cancer and AIDS, and the function of cells at the molecular level.
In addition to research, our faculty members teach post-doctoral and medical students. They are participants in the Advanced Tumor Virology course and SLU’s core graduate training program in biomedical sciences.
Our research efforts are founded on understanding:
- Mechanisms of cell transformation and growth control by DNA tumor viruses and retroviruses
- Molecular mechanisms involved in HIV-1 gene expression
- Regulation of eukaryotic cell proliferation by oncoproteins
- Molecular biology of eukaryotic cells
Emphasizing recombinant DNA and genetic engineering methods, our specific research programs include studies on:
- Molecular mechanisms of human adenovirus-induced cell transformation
- Regulation of viral genes, and the organization and functions of viral oncoproteins
- Molecular mechanisms involved in the regulation of human immunodeficiency virus
- Mechanisms of retrovirus integration; the mechanism of HIV-1-induced T cell destruction and HIV-1 pathogenesis
- Regulation of viral mRNA export in complex retroviruses
- Development of viral vectors for human gene therapy
Graduate Education at the Institute for Molecular Virology
Graduate students who enter the first-year core graduate program in the biomedical sciences at the Saint Louis University School of Medicine select a mentor for their Ph.D. dissertation research in their second year. All faculty at the Institute for Molecular Virology have graduate faculty status and have trained nearly two dozen students preparing for their Ph.D.
Students must meet the graduation requirements set forth by the Department of Molecular Microbiology and Immunology to obtain their Ph.D.
Institute for Molecular Virology Faculty
- Govindaswamy Chinnadurai, Ph.D.
- Duane P. Grandgenett, Ph.D.
- Ratna Ray, Ph.D.
- Thirugnana Subramanian, Ph.D.
- Sibes Bera, Ph.D.
- Krishan K. Pandey, Ph.D.
- Vijay Selvamani, Ph.D.