Susan E. Crawford, D.O.

Vice Chair for Research; Adjunct Professor
Pathology
Research


Education

D.O., Midwestern University (CCOM), Chicago, IL, 1987

Certifications

Illinois Medical License, 1986-current
B/E Anatomic Path/Pediatric Path

Research Interests

Clinical interests: Perinatal, cardiac and placental pathology
Research interests: Obesity & Cancer; Regulation of Angiogenic Mediators in the Tumor Microenvironment

Publications

PubMed Listing

Gattu, A.K., Birkenfeld, A.L., Jornayvaz, F., Dziura, J., Li, F., Crawford, S.E., Chu, X., Still, C.D., Gerhard, G.S., Chung, C., Samuel, V. Insulin resistance is associated with elevated serum pigment epithelium-derived factor (PEDF) levels in morbidly obese patients (2012) Acta Diabetologica, in press.

Grippo, P.J., Fitchev, P.S., Bentrem, D.J., Melstrom, L.G., Dangi-Garimella, S., Krantz, S.B., Heiferman, M.J., Chung, C., Adrian, K., Cornwell, M.L., Flesche, J.B., Rao, S.M., Talamonti, M.S., Munshi, H.G., Crawford, S.E. Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice (2012) Gut, in press.

Homan, E.P., Rauch, F., Grafe, I., Lietman, C., Doll, J.A., Dawson, B., Bertin, T., Napierala, D., Morello, R., Gibbs, R., White, L., Miki, R., Cohn, D.H., Crawford, S., Travers, R., Glorieux, F.H., Lee, B. Mutations in SERPINF1 cause osteogenesis imperfecta type VI (2011) Journal of Bone and Mineral Research, 26 (12), pp. 2798-2803.

Schmitz, J.C., Protiva, P., Gattu, A.K., Utsumi, T., Iwakiri, Y., Neto, A.G., Quinn, M., Cornwell, M.L., Fitchev, P., Lugea, A., Crawford, S.E., Chung, C. Pigment epithelium-derived factor regulates early pancreatic fibrotic responses and suppresses the profibrotic cytokine thrombospondin-1 (2011) American Journal of Pathology, 179 (6), pp. 2990-2999.

Tiwari, A.K., Crawford, S.E., Radosevich, A., Wali, R.K., Stypula, Y., Kunte, D.P., Mutyal, N., Ruderman, S., Gomes, A., Cornwell, M.L., Cruz, M.D.L., Brasky, J., Gibson, T.P., Backman, V., Roy, H.K. Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis (2011) Cancer Letters, 306 (2), pp. 205-213.

Subramanian, P., Crawford, S.E., Becerra, S.P. Assays for the antiangiogenic and neurotrophic serpin pigment epithelium-derived factor (2011) Methods in Enzymology, 499, pp. 183-204.

Chung, C., Mader, C.C., Schmitz, J.C., Atladottir, J., Fitchev, P., Cornwell, M.L., Koleske, A.J., Crawford, S.E., Gorelick, F. The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer (2011) Laboratory Investigation, 91 (5), pp. 732-743.

Yu, N., Kozlowski, J.M., Park, I.I., Chen, L., Zhang, Q., Xu, D., Doll, J.A., Crawford, S.E., Brendler, C.B., Lee, C. Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type I receptor (2010) Urology, 76 (6), pp. 1519.e8-1519.e13.

Fitchev, P.P., Wcislak, S.M., Lee, C., Bergh, A., Brendler, C.B., Stellmach, V.M., Crawford, S.E., Mavroudis, C.D., Cornwell, M.L., Doll, J.A. Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-β activation (2010) Laboratory Investigation, 90 (7), pp. 1078-1090.

George, M., Rainey, M.A., Naramura, M., Ying, G., Harms, D.W., Vitaterna, M.H., Doglio, L., Crawford, S.E., Hess, R.A., Band, V., Band, H. Ehd4 is required to attain normal prepubertal testis size but dispensable for fertility in male mice (2010) Genesis, 48 (5), pp. 328-342.

Professional Organizations and Associations

International Academy of Pathology