Grant R. Kolar, M.D., Ph.D.

Assistant Research Professor
Pathology

Director
Research Microscopy and Histology Core


Education

M.D., Ph.D., University of Oklahoma Health Sciences Center

Research Interests

Translational aspects of immunological and small peptide biology in diseases that impact the eye and brain

Publications

PubMed Listing

Samson WK, Stein LM, Elrick M, Salvatori A, Kolar G, Corbett JA, Yosten GL.  Hypoglycemia unawareness prevention: Targeting glucagon production. Physiol  Behav. 2016 Aug 1;162:147-50. doi: 10.1016/j.physbeh.2016.04.012. Epub 2016 Apr 11. Review. PubMed PMID: 27080082; PubMed Central PMCID: PMC4899234.

Marentette J, Kolar G, McHowat J. Increased susceptibility to bladder inflammation in smokers: targeting the PAF-PAF receptor interaction to manage inflammatory cell recruitment. Physiol Rep. 2015 Dec;3(12)PubMed PMID: 26660553.

Elrick MM, Samson WK, Corbett JA, Salvatori AS, Stein LM, Kolar GR, Naatz A, Yosten GL. Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic alpha cells. Am J Physiol Regul Integr Comp Physiol. 2015 Nov 11;PubMed PMID: 26561648.

Bauskar A, Mack WJ, Mauris J, Argüeso P, Heur M, Nagel BA, Kolar GR, Gleave ME, Nakamura T, Kinoshita S, Moradian-Oldak J, Panjwani N, Pflugfelder SC, Wilson MR, Fini ME, Jeong S.  Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye.  PLoS One. 2015. 10(9):e0138958. doi: 10.1371/journal.pone.0138958. eCollection 2015

Holecamp TF, Mollman ME, Murphy RKJ, Kolar GR, Morparia NP, Derdeyn CP, Moran CJ, Perrin RJ, Rich KM, Lanzino G, Zipfel GJ.  Dural arteriovenous fistula-induced thalamic dementia: report of 4 cases.  Journal of Neurosurgery.  2016 Jun;124(6):1752-65. doi:10.3171/2015.5.JNS15473. Epub 2015 Nov 20. PubMed PMID: 26587655.

Yosten GL, Kolar GR. The Physiology of Proinsulin C-Peptide: Unanswered Questions and a Proposed Model. Physiology (Bethesda). 2015 Jul;30(4):327-32. doi: 10.1152/physiol.00008.2015. Review. PubMed PMID: 26136546.

Yosten GL, Elrick MM, Salvatori A, Stein LM, Kolar GR, Ren J, Corbett JA, Samson WK. Understanding peptide biology: The discovery and characterization of the novel hormone, neuronostatin. Peptides. 2015 Jun 4. pii: S0196-9781(15)00167-9. doi: 10.1016/j.peptides.2015.05.011. [Epub ahead of print] PubMed PMID: 26051024.

Griffett K, Welch RD, Flaveny CA, Kolar GR, Neuschwander-Tetri BA, Burris TP. The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis. Mol Metab. 2015 Feb 9;4(4):353-7. doi:10.1016/j.molmet.2015.01.009. eCollection 2015 Apr. PubMed PMID: 25830098; PubMed Central PMCID: PMC4354919.

Richards JP, Yosten GL, Kolar GR, Jones CW, Stephenson AH, Ellsworth ML, Sprague RS.  Low O2-induced ATP release from erythrocytes of humans with type 2 diabetes is restored by physiological ratios of C-peptide and insulin. Am J Physiol Regul Integr Comp Physiol. 2014 Oct 1;307(7):R862-8.

Kolar GR, Kothari PH, Khanlou N, Jen JC, Schmidt RE, and Vinters HV.  Neuropathology and Genetics of Cerebroretinal Vasculopathies.  Brain Pathology. 2014;24:510.

Honors and Awards

University of Oklahoma Medical School Award in Geriatrics
Outstanding Graduate Student Award (University of Oklahoma)
Alpha Epsilon Lambda
Phi Kappa Phi

Professional Organizations and Associations

American Society for Investigative Pathology
College of American Pathology
American Society for Clinical Pathology
American Association of Ophthalmic Pathologists, Associate Member
American Association of Neuropathologists