Pediatric Cardiology Research

Clinical and translational research projects are a focus of Saint Louis University's pediatric cardiology division. Our faculty have been active in producing abstracts leading to regional and national presentations as well as published manuscripts in peer-reviewed journals.

Our faculty members also work closely with students and residents who are interested in carrying out clinical research projects.

Clinical and Research Interests

Kenneth Schowengerdt, Ph.D.

Kenneth Schowengerdt, Ph.D., serves as the division director of pediatric cardiology. His clinical responsibilities include inpatient and outpatient cardiology, and participation in non-invasive imaging. He is also the medical director of the Pediatric Heart Transplant Program.

His research interests include diagnosis and management of cardiomyopathy and heart failure; clinical cardiac transplantation; study of non-invasive methods of rejection surveillance; and investigation of immunologic mechanisms contributing to transplant vasculopathy. Dr. Schowengerdt is a Fellow of the American College of Cardiology, and a member of the American Pediatric Society and Society for Pediatric Research.

Jason Garnreiter, M.D.

Jason Garnreiter, M.D., is the director of pediatric electrophysiology. He specializes in the diagnosis and management of heart rhythm disorders, and performs procedures including cardiac ablations as well as pacemaker and defibrillator implantations. His research interests include inherited arrhythmias such as long QT syndrome, as well as pacemaker lead design and ways to optimize defibrillator programming for children and congenital heart disease patients. He is a member of the Heart Rhythm Society (HRS) and the Pediatric and Adult Congenital Electrophysiology Society (PACES).

Susan Haynes, M.D. 

Susan Haynes, M.D., specializes in non-invasive cardiology to include echocardiography, transesophageal echocardiography and fetal cardiology. Her research interests include fetal echocardiographic assessment of infants with congenital heart disease.

Saadeh Jureidini, M.D.

Saadeh Jureidini, M.D., is the director of the Cardiac Catheterization Laboratory. His clinical and research interests include interventional therapies and device placement; assessment of coronary artery flow dynamics by Doppler echocardiography and abnormal variations seen in congenital and acquired heart disease; efficacy of thrombolytic therapy for thrombosis of the heart and great vessels; and assessment of pulmonary hypertension.

Renuka Peterson, M.D.

Renuka Peterson, M.D., is the director of non-invasive imaging. She specializes in non-invasive cardiology to include echocardiography, transesophageal echocardiography and fetal cardiology. Her research interests include fetal echocardiographic assessment of infants with congenital heart disease.

Babak Rahimi, M.D.

Babak Rahimi, M.D., is the divisional coordinator of outpatient services. He also participates in the non-invasive imaging lab to include echocardiography and transesophageal echocardiography. His current research interest includes the identification and echocardiographic assessment of congenital coronary artery abnormalities.

Jamie Sutherell, M.D.

Jamie Sutherell, M.D., maintains clinical responsibilities within the outpatient cardiology clinic and noninvasive imaging lab. His primary clinical interest is echocardiography, especially transesophageal echocardiography. His specific teaching interest is curriculum development and evaluation. He serves as the associate director of pediatric education for the medical school and is a member of the clinical Simulation Education Team (SET).

Grants

Fleur Di Lis Grant
W. King, MD 
Co-PI, Fetal International Cardiac Registry
07/01/2014 – 06/30/2017

Publications

  • Bartlett HL, Lamers LJ, Haynes SE, Skorton DJ. Congenital Heart Disease in Adults> In Singh AK, editor. Scientific American Medicine [online]. Hamilton (ON): Decker Intellectual Properties; December 2015. Available at: http://www.sciammedicine.com

  • Danon S, Gray RG, Crystal MA, Morgan G, Gruenstein DH, Goldstein BH, Gordon BM. Expansion Characteristics of Stents Used in Congenital Heart Disease: Serial Dilation Offers Improved Expansion Potential Compared to Direct Dilation. Congenital Heart Disease, online publication June 2016.

  • Haynes SE, Saini S, Schowengerdt KO. Post-transplant Lymphoproliferative Disease and Other Malignancies After Pediatric Cardiac Transplantation: An Evolving Landscape. Curr Opin Organ Transplant 2015 Oct; 20(5):562-9.

  • Hirst CS, Jureidini S, Hauptman PJ. Arrhythmias in a Long-term Adult Survivor with Uncorrected Tetralogy of Fallot: Case Report and Review of the Literature. J Electrocardiol 2015 Jul-Aug; 48(4):734-8.

  • Moore JP, Wang S, Albers EL, Salerno JC, Stephenson EA, Shah MJ, Pflaumer A, Czosek RJ, Garnreiter JM, Collins K, Papez AL, Sanatani S, Cain NB, Kannankeril PJ, Perry JC, Mandapati R, Silva JN, Balaji S, Shannon KM. A Clinical Risk Score to Improve the Diagnosis of Tachycardia-Induced Cardiomyopathy in Childhood. Am J Cardiol, 2016, Jul 18.

  • Moore JP, Shannon KM, Fish FA, Seslar SP, Garnreiter JM, Krause U, Tanel Re, Papez AA, Pilcher TA, Balaji S. Catheter Ablation of Supraventricular Tachyarrhythmia After Extracardiac Fontan Surgery. Heart Rhythm 2016, Sep: 13(9): 1891-7.

  • Peterson RE, Haynes SE. Complete Atrioventricular Septal Defect With Truncus Arteriosus and Interrupted Aortic Arch in the Fetus. Echocardiography, 2016 Jun;33(6): 939-942. Epub 2016 Feb 22.

  • Rent S, Wehrmann M, Pugh K, and Peterson R. Persistent Cough and Hypoxia in a 5-Year-Old Girl with a History of Complex Congenital Heart Disease and Fontan Procedure. Pediatrics in Review. In press.

  • Simpson KE, Cunningham MW, Lee CK, Ward K, Tong A, Danon S, Simon C, Delaney JW, Canter CE. Autoimmunity Against the Heart and Cardiac Myosin in Children With Myocarditis. J Card Fail, Epub Mar 3, 2016.
  • Simpson KE, Storch GA, Lee CK, Ward KE, Danon S, Simon CM, Delaney JW, Tong A, Canter CE. High Frequency of Detection by PCR of Viral Nucleic Acid in the Blood of Infants Presenting With Clinical Myocarditis. Pediatr Cardiol, 2015, Oct 26.

Abstracts and Presentations

  • Aldoss O, Goldstein BH, Danon S, Williams D, Whiteside W, Sathanandam S, Gray R, Zampi JD. Acute and Mid-Term Outcomes of Stent Implantation for Recurrent Coarctation of the Aorta in Young Single Ventricle Patients Following the Norwood Operation: A Multi-Center PICES Investigation. Poster presented at the Pediatric and Adult Interventional Cardiac Symposium Annual Meeting in Las Vegas, NV, September 17-22, 2015.

  • Brueske K, Bauer C, Garnreiter J. Nearly Fluoroless Pacemaker Implantation in a Pregnant Pediatric Patient With Acquired Complete AV Block. Heart Rhythm Society Scientific Sessions, May 2016.

  • Buelter J, Parimi M, Thanugundla V, Condoor S, Parkar N, Danon S, King W. Feasibility and Validity of Printing 3-Dimensional Heart Models From Rotational Angiography. Pediatric Academic Societies, Baltimore, MD, Apr 30 – May 3, 2016.

  • Calamar N, Peterson R, Spence K. A Single Institution Experience of Cardiac Intervention in Infants With Trisomy 13 and 18. Poster presented at Pediatric Academic Societies Annual Meeting, Baltimore, MD, April 30-May 3, 2016.

  • Castleberry C, Amenduri R, Schowengerdt K, Edens E, Hagin N, Pruitt E, Kirklin J, Urschel S. Impact of Induction Therapy Type in High and Low Risk Pediatric Patients After Heart Transplant: Analysis of the PHTS Database. J Heart Lung Transplant 2016; 35(4S): S72. Presented at the International Society for Heart and Lung Transplantation Annual Meeting, Washington DC, April 27-30, 2016.

  • Davis E, Sutherell J. Outcomes of Interventions for Congenital heart Disease in Patients With Trisomy 18. Poster presented at the Midwest Pediatric Cardiology Society Annual Meeting, Peoria, IL, September 10-11, 2015.

  • Goel A, Fiore A, Schowengerdt K, Huddleston C. Temporary Inactivation From the Waitlist Due to Decline in Health Does Not Affect Mid-Term Outcomes Among Pediatric Heart Transplant Recipients. J Heart Lung transplant 2016; 35(4S): S404. Presented at the International Society for Heart and Lung Transplantation Annual Meeting, Washington DC, April 27-30, 2016.

  • Goel A, Fiore A, Schowengerdt K, Huddleston C. Developmental Delay is Not a Risk Factor for Poor Outcome in Pediatric Heart Transplantation. J Heart Lung Transplant 2016; 35(4S): S398. Presented at the International Society for Heart and Lung Transplantation Annual Meeting, Washington DC, April 27-30, 2016.

  • Kremer T, Hunter L, Hundley J, Fiore A, Huddleston C, Jureidini S, Danon S. Extracardiac Fontan Fenestration Device Closure: Acute Results and Mid-Term Follow up. Poster presented at the Pediatric and Adult Interventional Cardiac Symposium Annual Meeting in Las Vegas, NV, September 17-22, 2015.

  • Mitchell S, Schowengerdt K. Use of Echocardiography by Primary Care Physicians as a Mode of Cardiac Evaluation: Diagnostic Yield and Potential Effect on Cost of Care. Poster presented at Pediatric Academic Societies Annual Meeting, Baltimore, MD, April 30-May 3, 2016.

  • Mitchell S, Sutherell J. Noninvasive Management of a Right Atrial Thrombus Associated With a Central Line. Poster presented at the Midwest Pediatric Cardiology Society Annual Meeting, Peoria, IL, September 10-11, 2015.

  • Mitchell S, Sutherell J. Noninvasive Management of a Right Atrial Thrombus Associated With a Central Line. Poster presented at Pediatric Science Days, St. Louis, MO, Apr 21-22, 2016.

  • Parimi M, Buelter J, Thanugundla V, Condoor S, Parkar N, Danon S, King W. Feasibility and Validity of Printing 3-Dimensional Heart Models From Rotational Angiography. Poster presented at Pediatric Science Days, St. Louis, MO, Apr 21-22, 2016.

  • Parkar N, Moritz M, Condoor S, King W. Gateway to the Arch: 3D-printed Models in Three Case of Interrupted Aortic Arch. Radiological Societies of North America, Chicago, IL, Nov 29-Dec 4, 2015.

  • Petersen R, Danon S, Jureidini S. Novel Access to the Native Atria Following Total Cavopulmonary Anastomosis. Poster presented at the Pediatric and Adult Interventional Cardiac Symposium Annual Meeting in Las Vegas, NV, September 17-22, 2015.

  • Peterson R, Calamur N, Spence K. Outcomes After Cardiac Intervention in Infants With Trisomy 13 and 18. Poster presented at the American College of Cardiology 65th Annual Scientific Session, Apr 2-5, 2016, Chicago, IL.

  • Price B, Hundley J, Jureidini S, Danon S. Effects of Applying Radiation Dose Reduction Measures During Pediatric Cardiac Catheterization Procedures. Presented at the American College of Cardiology National Cardiovascular Data Registry (NCDR), Chicago, IL, March 2016.
  • Sutherell JS. "Reflective writing during a pediatrics clerkship". Poster at 2017 COMSEP (Council on Medical Student Education in Pediatrics) meeting, March 29 through April 1 in Portland, Oregon.
    Singleton L, DeWolfe C, Gigante J, Khidir A, Sutherell J, Jirasevijinda TJ. "Poster to Publication", presented at 2017 COMSEP Meeting.