SLUCare's DNA Diagnostic Laboratory offers a variety of tests that utilize molecular biology techniques for genetic, microbiological and oncological analysis. These techniques allow identification of gene rearrangements in neoplastic processes, detection of infectious agents and the direct detection of specific inherited mutations.
Southern blot and PCR offer highly specific and sensitive methods of detection in the evaluation of neoplasms. DNA analysis is available for biopsied samples of lymphoid, peripheral blood, bone marrow and other tumors in order to detect characteristic gene rearrangements and the activation of specific oncogenes.
For clinical microbiology, DNA diagnosis by PCR offers a highly specific and sensitive identification of pathogenic microorganisms, which may be especially difficult to culture in the clinical laboratory. Direct genetic diagnosis requires a specimen from the individual for detection or corroboration of a suspected inherited disorder.
The DNA Diagnostic Laboratory maintains an expanding list of tests. The staff also assists in sending samples to and interpreting results from other certifiable laboratories for tests not offered by our laboratory.
Hours of Operation
The DNA Diagnostic Laboratory is open 8 a.m. to 4:30 p.m. Monday through Friday.
DNA Available Tests
Prior arrangements with the laboratory may be necessary for special procedures or scheduling. For such arrangements, please contact the DNA Diagnostic Laboratory at (314) 577-8344 or, director of the DNA Laboratory, at (314) 577-8482.
Written reports with interpretation are generally available within two working weeks after the beginning of testing. Final reports are available online and are sent to the physician and added to the patient's chart; in addition the results of the assay can be accessed through Meditech in the Anatomic Pathology directory. HCV, K-RAS and EGFR results are located in the laboratory module of Meditech. Partial results and plans for further testing, if needed, are discussed by the director with the referring physician.