Purpose of the study:
Tularemia or "rabbit fever' is a disease of animals and humans. It is caused by a bacterium called Francisella tularensis (F. tularensis) found in rodents, rabbits and hares.
In the United States, about 200 people are reported to have tularemia each year, usually after exposure to a sick animal. It can also be spread through being bitten by an infected tick, deerfly or other insect, by drinking contaminated water, by eating contaminated food, or by breathing in the dust from soil or animal pelts that are infected.
Some laboratory workers may be at risk of getting tularemia ether by direct contact with infected animals or by breathing in the bacteria. Tularemia is not spread through person to person contact.
There is currently no licensed vaccine to treat tularemia. The availability of a vaccine may protect from the disease or may result in a milder disease and fewer complications.
The vaccines to be used in this study are considered to be a type of live vaccine strain (LVS). LVS vaccines are prepared using live bacteria or viruses that have been altered so they are weaker but keep their ability to fight infection.
LVS vaccines do not contain bacteria that can cause full-blown, severe disease
Important points regarding the study:
For more information about this study, please contact the Vaccine Center.
Please refer to Study #276.