The Department of Neurology and Psychiatry will host Grand Rounds in two different locations from 8-9 a.m. Thursday, April 7.
The neurology division session will be held in the SLU School of Medicine, 1402 So. Grand, Schwitalla Hall, lecture hall 1. The entrance is through the Learning Resource Center, 3544 Caroline Mall.
Heather MacArthur, Ph.D. will present "Parkinson's Disease(s): Different Pathways to the Same End-Point."
MacArthur is an associate professor in the Department of Pharmacological and Physiological Science at Saint Louis University School of Medicine.
MacArthur obtained her bachelor's degree in pharmacology from the University of Edinburgh, Scotland, and earned her doctorate in pharmacology from the William Harvey Research Institute, St. Bartholomew's Medical College, London.
She completed her post-doctoral research fellowship in the Department of Pharmacological and Physiological Science at Saint Louis University School of Medicine.
In 1997, Macarthur joined the faculty in the Department of Pharmacological and Physiological Science at Saint Louis University.
Her primary research interest is the role that reactive oxygen and nitrogen species have in modulating catecholaminergic signaling pathways. To date, her work has demonstrated the significance of this modulation in cell and healthy animal models, as well as in animal models of hypertension and septic shock. Most pertinent to this presentation is her work on the role played by oxidative stress in the neurodegeneration of central dopaminergic pathways associated with Parkinson's Disease.
Specifically, she has studied the effect of dopaminochrome, an oxidized form of dopamine, on neuronal cells derived from the midbrain region of mice, as well as in intact rats. Her work shows that dopaminochrome is indeed present in animal models of neurodegeneration and, when applied exogenously either in vitro or in vivo, is capable of causing neuronal cell death in a programmed manner.
MacArthur has received NIH funding for her research. She also has published more than 30 peer-reviewed articles and made multiple research presentations at both national and international scientific conferences.
The psychiatry division program will be held in Monteleone Hall, 1438 So. Grand Blvd., Classroom A, basement level. Entry is through the rear parking lot.
Ravinder Goswami, M.D., will present "Psychosis and Anti-Psychotic Medications. "
Goswami did his adult psychiatry residency training from University of Kansas in June 2010. He is an adjunct faculty at SLU since July 2010 as well as working in private practice with psych care consultant.