Department of Molecular Microbiology and Immunology
Saint Louis University Medical Center | Edward A. Doisy Research Center
Rm 716 | 1100 South Grand | St. Louis, Missouri 63104
Phone 314.977.8850 Fax 314.977-8717 | Email: email@example.com
Dr. Bill Wold, Chairman
Research in the Department of Molecular Microbiology and Immunology reflects the strength and diversity of its faculty through a unifying focus of the study of host-pathogen interactions, especially in the areas of virology and immunology.
The Department has state-of-the-art laboratories located in a newly constructed research and teaching complex together with other basic science departments in the School of Medicine.
The 10 primary and 15 secondary faculty in the Department have strong independent research programs funded by the government, research foundations, and industry. The faculty serve on national peer-review panels and journal editorial boards, are often invited to report on their work at other institutions, and their research is published in highly visible scientific journals. Students in the department receive progressive didactic instruction and extensive cutting-edge research training in virology, immunology, molecular biology, cell biology, and cell-cell interactions.
Research in the Department of Molecular Microbiology and Immunology reflects the strength and diversity of its faculty through a unifying focus of the study of host-pathogen interactions, especially in the area of virology.
General areas of interest include:
- viral pathogenesis
- molecular and cellular biology
The virology program is one of the strongest in the USA, and it encompasses research on:
- hepatitis B and C viruses
- Herpes simplex virus
- HIV (structure-function of integrase enzyme)
- poxviruses (including model studies for smallpox)
- anti-viral drug therapy
- cancer gene therapy using viral vectors
The immunology program includes research on:
- immunotherapy of cancer
- regulatory T cells in autoimmune disease
- molecular mechanisms that control regulatory T cells
- cytokine function
- vaccine development (discovery and clinical trials)
- nutrophils and natural killer cells
- parasites (T. cruzi)
- Mycobacterium tuberculosis
- cell cycle regulation
- programmed cell death (apoptosis)
- role of mitochondrial mutations in disease
- ultrasensitive detection of nucleic acids and proteins
Richard J. DiPaolo, Ph.D.
American Cancer Society awards $760,000 to researchers
The organization awarded $720,000 to Saint Louis University’s Richard DiPaolo to help fund his research in gastric cancer. DiPaolo studies how to reduce inflammation in the stomach and in turn, reduce the risk of developing cancer. He discovered that injecting of a specific type of cell called a “T regulatory cell” can suppress stomach inflammation.Read More>>>>>