Curriculum Vitae                        Brent M. Znosko

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Education

1995-1999     B.S., Chemistry, Emphasis in Biochemistry, Allegheny College, Meadville, PA
                       
Senior Thesis Title:  Thermodynamics of Single Nucleotide Bulges in RNA Duplexes
                       
Thesis Advisor:  Professor Martin J. Serra, Department of Chemistry

1999-2004     M.S, Ph.D., Chemistry, University of Rochester, Rochester, NY
                        Thermodynamic and Structural Properties of RNA Oligomers Containing Purine Rich Internal

                         Loops and DNA:RNA Hybrids with C5-Propynyl Substitutions

                        Research Advisor:   Professor Douglas H. Turner, Department of Chemistry



Faculty Appointment

2004-               Assistant Professor of Chemistry, Saint Louis University

 

Honors and Awards

 

1995-1999         Presidential Merit Scholar, four-year, partial scholarship, Allegheny College.

1995-1999         PPG Industries Foundation Community Scholar, four-year, partial scholarship.

1995-1998         Alden Scholar, Allegheny College.

1998-1999         Distinguished Alden Scholar, Allegheny College.

1999          Magna Cum Laude with Honors, Allegheny College.

1999-2004         Sherman Clarke Fellow, University of Rochester.

2002-2003         Elon Huntington Hooker Graduate Fellow, University of Rochester.

2003-2004          Agnes M. and George Messersmith Fellow, University of Rochester.

2004         W. D. Walters Teaching Award, University of Rochester.

2005          LI-COR Biosciences Genomics Education Matching Fund

2005          Saint Louis University Summer Research Award

2005          Saint Louis University Beaumont Faculty Development Fund

2005          Research Corporation Cottrell College Science Award

2006          Saint Louis University Beaumont Faculty Development Fund

2006          Sigma Xi Grant-in-Aid of Research (awarded to J. Badhwar, M. Sedabres, and S. Karri)

Abstracts and Presentations (Presenter is underlined and SLU undergrads are marked with an asterisk.)

19. *Wright, D. J., *Rice, J. L., Yanker, D. M., Znosko, B. M. Nearest neighbor parameters for inosine-uridine pairs located within RNA Watson-Crick helices. 61st southwest and the 57th southeast joint regional meetings of the American Chemical Society, Memphis, TN (Poster).

18. Znosko, B. M. Thermodynamic studies of naturally occurring secondary structure motifs in RNA oligonucleotides. Invited seminar at Truman State University, Kirksville, MO.

17. Znosko, B. M., Kennedy, S. D., Wille, P. C., Krugh, T. R., and Turner, D. H. Structural features and thermodynamics of the J4/5 loop from the Candida albicans group I intron. 2005 Gordon Research Conference on Nucleic Acids (Poster).

16. *Wright, D. J., *Rice, J. L., and Znosko, B. M. Thermodynamic parameters of RNA duplexes containing inosine. 2005 Gordon Research Conference on Nucleic Acids (Poster).

15. Znosko, B. M., Kennedy, S. D., Wille, P. C., Krugh, T. R., and Turner, D. H. Structural features and thermodynamics of the J4/5 loop from the Candida albicans group I intron. RNA 2005: Tenth Annual Meeting of the RNA Society (Poster).

14. *Wright, D. J., *Rice, J. L., and Znosko, B. M. Thermodynamic parameters of RNA duplexes containing inosine. RNA 2005: Tenth Annual Meeting of the RNA Society (Poster).

13. *Wright, D. J., *Rice, J. L., and Znosko, B. M. Thermodynamic parameters of RNA duplexes containing inosine. 2005 Undergraduate Research Symposium sponsored by the St. Louis Section of the ACS. Awarded first place in the poster category (Poster).

12. Znosko, B. M., Kennedy, S. D., Wille, P. C., Krugh, T. R., and Turner, D. H. Structural features and thermodynamics of the J4/5 loop from the Candida albicans intron. Saint Louis University Biology Department 2005 Seminar (Talk).

11. Chen, G., Znosko, B. M., Kennedy, S. D., Jiao, X., Krugh, T. R., and Turner, D. H. Improved thermodynamic model for predicting RNA 3x3 internal loops and NMR structure of an unusually stable loop with three consecutive sheared GA pairs. 2004 Biological CHemistry Cluster in Department of Chemistry at the University of Rochester (Poster).

10. Znosko, B. M., Kennedy, S. D., Wille, P. C., Krugh, T. R., and Turner, D. H. Structural features and thermodynamics of the J4/5 loop from the Candida albicans intron. Sigma Xi Saint Louis University Chapter Fall 2004 Research Symposium (Poster).

9. Ferrin-O’Connell, I., Bellows, B., Znosko, B. M., Grover, N., and Turner, D. H. Examining the thermodynamic stability and metal binding properties of domain II of the hammerhead ribozyme. 2004 Nucleic Acid Gordon Conference (Poster).

8. Ferrin-O'Connell, I., Znosko, B. M., Grover, N., and Turner, D. H. Thermodynamics of hammerhead domain II oligonucleotide mimics. 2003 Rochester Research Experience for Undergraduates Poster Session (Poster).

7. Wille, P., Znosko, B. M., Krugh, T. R., and Turner, D. H. Thermodynamic and structural determination of the Candida albicans 2x2 internal loop. 2003 Rochester Research Experience for Undergraduates Poster Session (Poster).

6. Znosko, B. M., Barnes, T. W., Krugh, T. R., and Turner, D. H. NMR studies of DNA single strands and DNA:RNA hybrids with and without 1-propynylation at C5 of oligopyrimidines. Upstate New York Structural Biology Day 2003 (Talk).

5. Znosko, B. M., Burkard, M. E., Barnes, T. W., Schroeder, S. J., Krugh, T. R., and Turner, D. H. Providing structural insights into the thermodynamics of oligonucleotides: Purine-rich internal loops and propynylated systems. 2002 Rochester Biophysical Seminar (Talk).

4. Znosko, B. M. Thermodynamic and structural studies of purine rich internal loops. Rochester RNA Structure and Function Cluster Meeting 2002 (Talk).

3. Serra, M. J., Silvestri, S. B., Volkman, H., Boswell, B., and Znosko B. M. Thermodynamic parameters for RNA bulge formation. 2002 National Meeting of the American Chemical Society (Poster).

2. Skelly, K., Znosko, B. M., Krugh, T. R. Synthesis and thermodynamics of six-nucleotide RNA hairpin loops. 2001 Rochester Research Experience for Undergraduates Poster Session (Poster).

1. Znosko, B. M., and Serra, M. J. Thermodynamics of single nucleotide bulges in RNA duplexes. 1999 National Conference of Undergraduate Research (Poster).