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10-018 - Peptides for inducing heterosubtypic influenza T cell responses


Daniel F. Hoft


This invention provides compositions and methods for generation of an anti-influenza immune response. In particular, conserved T cell epitopes within matrix protein and nucleoprotein components of influenza virus have been identified and further screened for those structures that will bind either or both of HLA I and II molecules. Methods for vaccinating subjects with formulations of such peptides for the treatment or prevention of influenza infection also are described.

Intellectual Property Status

  • U.S. patent 9,265,822