Saint Louis University

Adjunct Professor of Health Care Ethics, Saint Louis University
Professor of Medicine, Washington University School of Medicine


James DuBois, PhD, DScJames DuBois is Professor of Medicine, Principal Investigator of the Professional and Social Issues Lab, and Director of the Center for Clinical and Research Ethics at Washington University School of Medicine, and an Adjunct Professor in the Albert Gnaegi Center for Health Care Ethics at Saint Louis University, where he was the inaugural Hubert Mäder Professor of Health Care Ethics and Director of the Bander Center for Medical Business Ethics. He is the founding Editor (with Ana Iltis) of Narrative Inquiry in Bioethics: A Journal of Qualitative Research, published by Johns Hopkins University Press. He completed his PhD in philosophy at the International Academy of Philosophy in Liechtenstein and his DSc in psychology at the University of Vienna. In 2010, he received the Society of Research Administrator's International Rose Award for best publication. He directs the Professionalism and Integrity in Research Program (PI Program), which offers intensive professional development education for researchers who have had difficulties with regulatory compliance. The PI Program won the 2013 Innovation in Human Research Protections from the Health Improvement Institute.

His research interests include research ethics in mental health, preventing wrongdoing in healthcare, ethics in organ transplantation, moral development and education, and empirical research on ethical issues.

He has served on numerous national committees on organ transplantation, including: the Institute of Medicine's committee on increasing rates of organ donation; the Canadian Council for Donation and Transplantation's Forum on Donation after Cardiac Death; the United Network for Organ Sharing's Regional Review Board for Livers; and Mid-America Transplant Services' committee for non-heart-beating organ donation. In the area of research ethics, he serves on a National Institute of Drug Abuse Data Safety Monitoring Board and is a member of the NIH study section on Social and Ethical Issues in Research. He is also a member of the Institutional Review Board and Ethics Committee at St. Anthony's Medical Center in St. Louis.


Scholarly Grants & Contracts

"Validating Outcome Measures for Remediation of Research Wrongdoing," $277,700 funded by the US Office of Research Integrity (1 ORIIR130002-01-00), September 1, 2013 – August 31, 2015. Principal Investigator. 

This project involves developing assessment instruments for RCR and remediation training programs, validating the instruments, establishing normative scores, and assessing pre- and post-test scores for the P.I. Program, which offers remediation training for investigators.

“Preventing Ethical Disasters in the Practice of Medicine,” $1,200,000 funded by the NIH National Institute of Aging, June 1, 2013 – May 31, 2018. Principal Investigator. 

This project will examine 300 cases of wrongdoing in medicine, including fraudulent unnecessary procedures, sexual abuse of patients, and improper prescribing of narcotics to identify predictive factors.

"Restoring Professionalism and Integrity in Research (RePAIR)," $500,000 funded by NIH (Administrative Supplement to WU ICTS). September 17, 2007-May 31, 2012. 

DuBois is serving as Project Director for this project and PI of the SLU subaward ($476,564). The project involves developing a curriculum for a remediation training program for investigators caught violating the rules for the responsible conduct of research.

"ORI Research Integrity Casebook," $155,579 funded by the Office of Research Integrity . March 1, 2011-September 30, 2012.

The major goal of this project is to produce a casebook that is suitable for use in face-to-face training in the responsible conduct of research.

"Environmental Factors Predictive of Misbehavior in Collaborative Health Research," National Institutes of Health (1R21RR026313-01). 9/25/2009-8/31/2010. $376,000. Principal Investigator.

"Environmental Factors Associated with Professional Misconduct in Medical Research and Practice," BF Foundation. 1/1/2009-12/31/2011. $100,000. Principal Investigator.

"Responsible Conduct of Research Instructional Assessment Program. Part II," Office of Research Integrity, Contract, 7/1/2008-9/30/2009. $60,000, Principal Investigator.

"Center for Clinical Research Ethics," within the Washington University of St. Louis, Institute for Clinical and Translational Science. (NIH: 1 U54 RR023496-01A1, Principal Investigator: Polonsky, K.) 9/1/2007-8/31/2012. Role: 15% effort as Director. $500,000 subcontract with St. Louis University, DuBois, Principal Investigator.

"Best Practices in Mental Health Research Ethics Conference Series," National Institute of Mental Health (1R13MH079690). 9/1/2007 - 8/31/2011. $200,000. Principal Investigator.

"Lay and Professional Attitudes Toward Uncontrolled Donation after Circulatory Determination of Death: A Pilot Study", Greenwall Foundation, $52,000. 7/1/2007-6/30/2008. Principal Investigator.

"Responsible Conduct of Research Instructional Assessment Project," Office of Research Integrity, Responsible Conduct of Research Resource Development Program, 06/01/06 - 10/31/07, $50,000. Principal Investigator.

"Behavioral Health Research: An Ethics Case Compendium and Instructional Method," Office of Research Integrity, Responsible Conduct of Research Resource Development Program, 9/01/03 - 8/31/04, $25,000 direct costs. Principal Investigator. See for emerging products.

"Ethical Issues in Behavioral Health Research," National Institute of Health, 1 T15 HL072453-01, 9/27/02 - 9/26/05, $527,961 direct costs. Principal Investigator. See for information on the training program.

"Lay Attitudes Toward Death Criteria and Organ Procurement. A Structured Interview Study." 10/1/2000 - 9/30/2001. $15,000 from Quest for the Gift of Life Foundation for joint project with Intermountain Donor Services. Principal Investigator.

Viktor Frankl Institute of Logotherapy, Abilene, TX. $9,200 grant to produce translation of Viktor Frankl's Theorie und Therapie der Neurosen, (Munich: Reinhardt, 1993, original 1967).

Beaumont Faculty Development Fund. Submitted March 1998. $5,000. Study entitled: "Prolonging and Shortening Life: An International Study on the Moral Reasoning of Medical Personnel". Principal Investigator.

SALUS CENTER,   3545 LAFAYETTE,   ST. LOUIS, MO 63104-1314   |   P: 314.977.1060   F: 314.977.5150