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Anya Hillery, Ph.D.


Department of Health Sciences, Nursing and Public Health


Education

B.Sc. (Pharmacy) (First Class Honours; awarded the Trinity College Gold Medal for Outstanding Achievement), School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland.
Ph.D. (Pharmaceutics), Centre for Drug Delivery Research, University College London School of Pharmacy, Brunswick Square, London, UK.

Practice Areas

  • Drug delivery systems
  • Drug targeting
  • Liposomes

Research Interests

The Wellcome Trust. Project Grant (£160,000).
The development of synthetic peptide vaccines, using a novel polymeric vaccine-adjuvant conjugate based on lipoamino acids.

The Wellcome Trust. New Lecturers Grant (£61,010)
Particle-forming properties of lipoamino acid - based systems and their potential use as particulate carriers for oral vaccination using peptide antigens.

Libyan Government. Research Studentship (£60,000)
Formulation of novel anaesthetic gels for bladder catheterisation.

Publications and Media Placements

Books

Drug Delivery: Fundamentals and Applications, Second Edition
Hillery AM, Park K, (eds.) 2016.
CRC Press/Taylor & Francis Group. Boca Raton, Florida.
ISBN 978-1482217711

Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists
Hillery AM, Lloyd AW, Swarbrick J, (eds.) 2001.
Taylor and Francis, London.
ISBN 0-415-27197-5.

Journal Articles: Original Research

Hillery AM, Jani PU, Florence AT. Comparative quantitative study of lymphoid and non- lymphoid uptake of 50nm polystyrene particles. J Drug Target 1994; 2: 151-156.

Toth I, Hillery AM, Wood I, Magnusson C, Artursson P. Oral absorption of lipidic amino acid conjugates. Int J Pharm 1994; 102: 223-230.

Toth I, Flinn N, Hillery AM, Artursson P. Lipidic conjugates of luteinizing hormone releasing hormone (LHRH) and thyrotropin releasing hormone (TRH) that release and protect the native hormones in homogenates of human intestinal epithelial (Caco-2) cells. Int J Pharm 1994; 105: 241-247.

Toth I, Hillery AM, Hughes RA, Dekany G, Ward P. Lipidic Peptides XV. Synthesis and oral uptake studies of lipidic and glyco-lipidic conjugates of ß-lactam antibiotics. Lieb Ann Chem. 1994; 7: 685-688.

Flinn N, Danton M, Hillery AM, Wood I, Gibbons WA, Toth I. A lipidic amino acid based carrier adjuvant system for drug delivery and for enhancing synthetic peptide immunogenicity. Biochem Soc Trans 1994; 22: 1055-1058.

Florence AT, Hillery AM, Hussain N, Jani PU. Oral uptake and translocation of nanoparticles: a real but useful phenomenon? In: Gregoriadis G, McCormack B, Poste G. eds. Targeting of Drugs: Advances in System Constructs. New York: Plenum Press, 1994, pp 173-181.

Florence AT, Hillery AM, Hussain N, Jani PU. Factors affecting the oral uptake and translocation of polystyrene nanoparticles: histological and analytical evidence. J Drug Target 1995; 3: 65-70.

Florence AT, Hillery AM, Hussain N, Jani PU. Nanoparticles as carriers for oral peptide absorption: studies on particle uptake and fate. J Control Rel 1995; 36: 39-46.

Hillery AM, Florence AT. The effect of adsorbed poloxamer surfactants on the intestinal uptake of 60 nm polyetyrene particles after oral administration in the rat. Int J Pharm 1996; 132: 123-130.

Hillery AM, Toth I, Florence AT. Co-polymerised peptide particles (CPP) I: synthesis, characterization and in vitro studies on a novel oral nanoparticulate delivery system. J Control Rel 1996; 41: 271-281.

Hillery AM, Toth I, Florence AT. Co-polymerised peptide particles (CPP) II: oral uptake of a novel co-polymeric LHRH nanoparticulate delivery system. J Control Rel 1996; 42: 65-73.

Hillery AM, Toth I, Florence AT. Biological activity of luteinizing hormone releasing hormone after oral dosing with a novel delivery system: Co-Polymerized Peptide Particles (CPP). Pharm Sci 1996; 2: 281-283.

Drouillat B, Hillery AM, Dekany G, Falconer R, Wright K, Toth I. Novel liposaccharide conjugates for drug and peptide delivery. J Pharm Sci 1998; 87:25-30.

Journal Review Articles

Hillery AM, Supramolecular lipidic drug delivery systems: from laboratory to clinic. A review of the recently introduced commercial liposomal and lipid-based formulations of amphotericin B. Adv Drug Del Rev 1997; 24:345-363.

Hillery AM, Continuous v. discontinuous therapy. Pharm Sci Technolo Today. Apr 1998; 1 (1).

Hillery AM, Microparticulate delivery systems: potential drug/vaccine carriers via mucosal routes. Pharm Sci Technol Today. May 1998; 1 (2).

Hillery AM, Liposomal drug delivery (I) Introduction. Pharm J; Oct 1998; 626-629.

Hillery AM, Liposomal drug delivery (II) Clinical Applications. Pharm J; Oct 1998; 712-715.

Hillery AM, Novel vaccine strategy demonstrates potential for Alzheimer's disease. Pharm Sci Technol Today. Sept 1999; 2 (9).

Hillery AM, New therapeutic options for HIV patients. Pharm Sci Technol Today. Oct 1999; 2 (10).

Hillery AM, Tumour-killing herpes simplex virus - a promising new approach for brain cancer. Pharm Sci Technolo Today. Oct 1999; 2 (10).

Hillery AM, Haemophilia B gene therapy using adeno-associated virus. Pharm Sci Technol Today. Nov 1999; 2 (11).

Hillery AM, Anti-vascular targeting: a novel approach to cancer treatment. Pharm Sci Technolo Today. Jan 2000; 3 (1).

Hillery AM, New implant device for Alzheimer's treatment. Pharm Sci Technol Today. Feb 2000; 3 (2).

Hillery AM, BioArtificial Muscle implants as drug delivery systems. Pharm Sci Technolo Today. March 2000; 3 (3).

Hillery AM, New liposomal formulation of vincristine for non-Hodgkin's lymphoma. Pharm Sci Technol Today. March 2000; 3 (3).

Hillery AM, Computer-integrated drug design provides new leads for thromboembolic disorders. Pharm Sci Technol Today. April 2000; 3 (4).

Hillery AM, New first-line monotherapy for epilepsy. Pharm Sci Technol Today. May 2000; 3 (5).

Hillery AM, Mouse model for Burkitt's lymphoma will aid understanding and therapy. Drug Discov Today. Jan 2001; 6 (1).

Hillery AM, Targeting ‘good' cholesterol to treat heart disease. Drug Discov Today. Feb 2001; 6 (3).

Hillery AM, Heat-sensitive liposomes for tumour targeting. Drug Discov Today. March 2001; 6 (5).

Honors and Awards

Maplethorpe Fellowship Award in the Pharmaceutical Sciences (1/10/1994): 2 years funding for post-doctoral investigations.

Controlled Release Society Award: best presentation at the UK CRS Symposium on Controlled Drug Delivery (8/1/1996).

Syntex Research (UK) Ltd: PhD Scholarship Award (1/10/1991).

Trinity College Gold Medal for Outstanding Achievement: best overall results in Trinity College Dublin 1990 Final-Year Examinations (1/7/1990).

Janssen Silver Medal: best final-year project (on the action of blockers at the neuromuscular junction) in the BSc (Pharmacy) Examinations (1/7/1990).