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Adam D. Farmer, M.D., Ph.D., FRCP(UK)

Professor, Division of Gastroenterology and Hepatology
Department of Internal Medicine

Research Interests

Farmer leads a research program focused on novel neuromodulatory treatments. He is also interested in the gastroenterological manifestations of systemic disorders such as diabetes and Ehlers-Danlos Syndrome.

Publications and Media Placements

Farmer has published more than 130 peer-reviewed papers, contributed to 20 medical textbooks, and been cited more than 14,000 times by other researchers. His H-index is 47.
 
Opioid Induced Constipation: Mechanisms and Management, Becker E, Madi MY, Magee M, Ansari N, Ruffle JKR, Syn WK, Drewes AM, Farmer AD, Postgraduate Medical Journal 2025, in press.
 
The Impact of Opioid Use in Chronic Pancreatitis from 2004-2024: A Propensity-Matched Analysis of 183,214 individuals, Kilani Y, Madi MY, Obeid Y, Heis F, Jiwon P, Mosquera D, Nammour T, Drewes AM, Olesen SS, Farmer AD, Pancreatology 2025, in press.
 
Dietary Management of Chronic Constipation in Adults Dimidi E, van Der Schoot A, Barrett K, Farmer AD, Lomer MC, Scott SM, Whelan K, Neurogastroenterology and Motility 2025, in press.
 
British Dietetic Association Guidelines for the Dietary Management of Chronic Constipation in Adults Dimidi E, van Der Schoot A, Barrett K, Farmer AD, Lomer MC, Scott SM, Whelan K, Journal of Human Nutrition and Dietetics 2025, in press.
 
Can symptoms and medical history predict outcomes for hydrogen and methane breath testing? Haworth JJ, Treadway S, Bloor S, Isaac K, Morrison J, Farmer AD, Hobson AR, American Journal of Gastroenterology 2025, in press.
 
Effect of stress, vagus nerve stimulation and disease activity on circulating cytokines in ulcerative colitis, Mogilevski T, Takahashi K, Smith R, Hardy M, Tye-Done J, Farmer AD, Aziz Q, Gibson PR, Journal of Gastroenterology and Hepatology Open 2025, in press.
 
The Impact of Cannabis Use in Gastroparesis: A Propensity Matched Analysis of 40,670 gastroparesis patients, Kilani Y, Mosquera D, Puelo P, Aldiabat M, Ruffle JK, Mahmoud M, Farmer AD, American Journal of Gastroenterology 2025, in press.
 
Young people’s priorities for the self-management of distress after stoma surgery due to inflammatory bowel disease: a consensus, Saunders B, Polidano K, Bray L, Fisher T, Corp N, Mc Dermott Hughes M, Farmer AD, Morris B, Fleetwood Beresford S, Chew Graham C, Health Expectations 2024; 27(2): e14009.
 
Healthcare professionals’ priorities for training to identify and manage distress experienced by young people with a stoma due to inflammatory bowel disease: a consensus study using online nominal group technique, Saunders B, Polidano K, Chew-Graham CA, Fisher T, Corp N, McDermott Hughes, M, Farmer AD, Bray L, BMJ Open 2023;13:e072360.
 
Recommendations for the management of opioid-induced constipation - how to improve usability in clinical practice, Okdahl T, Farmer AD, Emmanuel A, Morlion B, Varrassi E, Drewes AM, Expert Reviews Gastroenterology and Hepatology 2023; 17 (10): 975 – 983.
 
Patients' views and experiences of delayed diagnosis of inflammatory bowel disease: a qualitative study, Cross E, Prior JA, Farmer AD, Saunders B, British Journal of General Practice 2023, 7 (4) BJGPO.2023.0070.
 
Diagnostic delay in adult inflammatory bowel disease: A systematic review, Cross E, Saunders B, Farmer AD, Prior JA. Indian J Gastroenterol. 2023 Feb;42(1):40-52.
 
The analysis of gut microbiota in patient with bile acid diarrhoea treated with colesevelam, Kumar A, Quarashi M, Al-Hassi H, El-Asrag M, Segal JP, Jain M, Steed H, Butterworth J, Farmer AD, McLaughlin J, Beggs A, Brookes MJ, Frontiers in Microbiology 2023, 14: 1134105.
 
Randomised, Placebo-controlled Trial and Meta-analysis show benefit of Ondansetron for Irritable Bowel Syndrome with Diarrhoea; The TRITON trial, Gunn D, Lalani R, Fried R, Corsetti M, Scott SM, Farmer AD, Kapur K, Sanders DS, Eugenicos M, Akbar A, Aziz Q, Ford AC, Spiller RC, Alimentary Pharmacology and Therapeutics 2023, 57(11):1258-1271.
 
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis, Abani O, et al. Farmer AD, et al., Lancet 2022; 400(10358):1102. doi: 10.1016/S0140-6736(22)01866-9.
 
Factors Influencing Rectal Hypersensitivity in Irritable Bowel Syndrome: A systematic review and meta-analysis, Roberts C, Albusoda A, Farmer AD, Aziz Q, Neurogastroenterology and Motility 2022, 35(4): e14515.
 
Intra-sphincteric botulinum toxin in the management of functional biliary pain, Menon S, Holt A, Farmer AD, Endosc Int Open. 2022 Apr 14;10(4):E521-E527. doi: 10.1055/a-1784-0061.
 
Performance and Interpretation of Hydrogen and Methane Breath Testing Impact of North American Consensus Guidelines. Pitcher C, Farmer AD, Treadway S, Hobson AR, Digestive Diseases Sciences 2022, 67(12):5571-5579.
 
Emotional modulation of visceral pain is associated with fear of pain and serotonergic polymorphisms, Weltens N, Brunner-Schaub N, Farmer AD, Aziz Q, Wahl V, Niesler B, Tack J, Van Oudenhove L, Coen SJ, Journal of Neurogastroenterology and Motility 2022, in press.
 
Diagnostic delay in paediatric inflammatory bowel disease: a systematic review, Cross E, Matoi S, Farmer AD, Saunders B, Prior J, Digestive Diseases and Sciences 2022, 67(12):5444-5454.
 
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia, Lucas Wauters, Ram Dickman, Vasile Drug, Agata Mulak, Jordi Serra, Paul Enck, Jan Tack, Anna Accarino, Giovanni Barbara, Serhat Bor, Benoit Coffin, Maura Corsetti, Heiko De Schepper, Dan Dumitrascu, Adam Farmer et al. UEG Journal 2021; doi.org/10.1002/ueg2.12061.
 
The autonomic brain: multi-dimensional generative hierarchical modelling of the autonomic connectome, Ruffle JK, Fitzke H, MacKay J, Lobo MD, Apkarian V, Farmer AD, Aziz Q, Cortex 2021, 143:164-179.
 
Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis, Brock C, Rasmussen SE, Drewes AM, Møller HJ, Brock B, Deleuran B, Farmer AD, Pfeiffer-Jensen M, Mediators Inflamm. 2021 May 27;2021:9933532.
 
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial, Abani O, et al. Farmer AD, et al., Lancet 2021; 397: 1637-1645.
 
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial, Abaleke E et al. Farmer AD et al, Lancet 2021; 397: 605-612.
 
Rectal hypersensitivity in inflammatory bowel disease: a systematic review and meta-analysis, Roberts C, Albusoda A, Farmer AD*, Aziz Q*, Crohn’s and Colitis 360 2021, 23;3(3):otab041. * Joint senior author.
 
British Society Guidelines on the Management of Irritable Bowel Syndrome, Vasant D, Paine PA, Black CJ, Houghton LA, Everitt HA, Corsetti M, Agrawal A, Aziz I, Farmer AD, Eugenicos M, Moss Morris R, Yiannakou Y, Ford AC, Gut 2021, 70(7):1214-1240.
 
Blood Test Monitoring of Immunomodulatory Therapy in Inflammatory Bowel Disease, Spencer NJ, Fryer AA, Farmer AD, Duff CJ, British Medical Journal 2021, doi: 10.1136/bmj.n159.
 
Access to Psychological Support for Young People Following Stoma Surgery: Exploring Patients’ and Clinicians’ Perspectives, Polidano K, Chew Graham CA, Farmer AD, Saunders B, Qualitative Health Research 2021, 31(3):535-549.
 
Short-term transcutaneous non-invasive vagus nerve stimulation may reduce disease activity and pro-inflammatory cytokines in rheumatoid arthritis: results of a pilot study, Drewes AM, Brock C, Rasmussen SE, Moller HJ, Deleuran BW, Farmer AD, Pfeiffer-Jensen M, Scandinavian Journal of Rheumatology 2021, 50(1): 20-27.
 
Chronic constipation in adults: contemporary perspectives and clinical challenges, Scott SM, Simrén M, Farmer AD, Dinning PG, Carrington EV, Benninga MA, Burgell RE Dimidi E, Fikree A, Ford AC, Fox M, Hoad CL, Knowles CH, Krogh K, Nugent K, Remes-Troche JM, Whelan K, Corsetti M, Neurogastroenterology and Motility 2021, doi: 10.1111/nmo.14050
 
Constipation predominant irritable bowel syndrome and functional constipation are not discrete disorders: a machine learning approach, Ruffle JK, Tinkler L, Emmett C, Ford AC, Nachev C, Aziz Q, Farmer AD*, Yiannakou Y*, American Journal of Gastroenterology 2021, 116(1):142-151.* Joint senior authors
 
Outcomes of Percutaneous Coronary Intervention in Patients with Crohn’s Disease and Ulcerative Colitis, Kobo O, Mohamed MO, Farmer AD, Alraies CM, Patel T, Sharma K, Nolan J, Bagur R, Roguin A, Mamas MA, American Journal of Cardiology 2020, 130:30-36.
 
International Consensus Based Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation, Farmer AD, Strzelczyk A, Finisguerra A, Gourine AV, et al., Koenig J, Frontiers in Human Neuroscience 2020, 23;14:568051.
 
European Society for Neurogastroenterology and Motility (ESNM) recommendations for conducting gastrointestinal motility and function testing in the recovery phase of the COVID-19 pandemic, Tack J, Vanuytsel T, Serra J, Accarino A, Barbara G, Azpiroz F, Bor S, Dickman R, Drewes AM, Drug V, Enck P, Farmer AD, Hauser G, Mulak A, Novais L, Medicas L, Pohl D, Davarino E, Storonova O, Zerbib F, Carbone F, Neurogastroenterology and Motility 2020, 32(7):e13930.
 
Transcutaneous vagus nerve stimulation prevents the development of, and reverses established, oesophageal pain hypersensitivity, Farmer AD, Albusoda A, Amersinghe A, Ruffle JK, Fitzke H, Idrees R, Fried R, Brock C, Aziz Q, Alimentary Pharmacology and Therapeutics 2020, 52(6):988-996.
 
Gastrointestinal symptoms and cardiac vagal tone in type 1 diabetes correlates with gut transit times and motility index, Brock C, Ejskjaer N, Karmisholt JS, Jakobsen PE, Drewes AM, Brock B, Farmer AD, Wegeberg AML, Hansen CS, Farmer AD, Neurogastroenterology and Motility 2020, doi: 10.1111/nmo.13885.
 
Liraglutide accelerates colonic transit in people with type 1 diabetes and polyneuropathy: A randomised, double-blind, placebo-controlled trial, Wegeberg AML, Hansen CS, Farmer AD, Karmisholt J, Drewes AM, Jakobsen PE, Brock B, Brock C, UEG Journal 2020, 8(6):695-704.
 
Association between opioid usage and rectal dysfunction in constipation: a cross-sectional study of 2754 patients, Vollebregt P, Knowles CH, Farmer AD, Scott SM, Neurogastroenterology and Motility 2020, 32(7):e13839.
 
An approach to the care of patients with irritable bowel syndrome, Farmer AD, Wood E, Ruffle JK, Canadian Medical Association Journal 2020, 192(11): E275-E282.
 
Non-invasive vagus nerve stimulation – hope or hype? Farmer AD, Neurogastroenterology and Motility 2020, doi.org/10.1111/nmo.13822.
 
Critical evaluation of animal models of visceral pain for therapeutic development: a focus on irritable bowel syndrome, Johnson AC, Farmer AD, Ness TJ, Greenwood-Van Mererveld B, Neurogastroenterology and Motility 2020, doi: 10.1111/nmo.13776.
 
The anatomical basis for transcutaneous auricular vagus nerve stimulation: a review, Butt MF, Albusoda A, Farmer AD, Aziz Q, The Journal of Anatomy 2020, 236(4):588-611.
 
Gastrointestinal pain, Drewes AM, Olesen AW, Farmer AD, Szigethy E, Rebours V, Olesen SS, Nature Reviews Disease Primers 2020, 32(7):e13839.
 
In-hospital Upper Gastrointestinal Bleeding Following Percutaneous Coronary Intervention, Kwok CS, Sirker A, Farmer AD, Kontopantelis E, Potts J, Ul Haw MA, Ludman P, de Belder M, Townend J, Zaman A, Large A, Kinnaird T, Mamas MA, Catheterization and Cardiovascular Interventions 2020, 95(1):109-117.
 
Liraglutide Treatment Reduced interleukin-6 in Adults With Type 1 Diabetes but Did Not Improve Established Autonomic or Polyneuropathy, Brock C, Hansen CS, Karmisholt J, Møller JH, Juhl A, Farmer AD, Drewes AM, Riahi S, Lervang HH, Jakobsen PE, Brock B, British Journal of Clinical Pharmacology 2019; 85(11):2512-2523.
 
Embracing a 'new normal': the construction of biographical renewal in young adults' narratives of living with a stoma, Polidano K, Chew Graham CA, Bartlam B, Farmer AD, Saunders B, Sociology Health Illness 2019; doi: 10.1111/1467-9566.13005
 
Continuous or Intermittent? Which Regimen of Enteral Nutrition is Better for Acute Stroke Patients? a Systematic Review and Meta-Analysis, Giovanni Di Paolo G, Twomlow E, Hanna FWF, Farmer AD, Lancaster J, Sim J, Roffe C, Online Journal of Neurology and Brain Disorders 2019. DOI : 10.32474/OJNBD.2019.03.000163
 
Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study protocol for a randomised controlled trial, Gunn D, Fried R, Lalani R, Farrin A, Holloway I, Morris T, Olivier C, Kearns R, Corsetti M, Scott SM, Farmer A, Emmanuel A, Whorwell P, Yiannakou Y, Sanders D, Mclaughlin J, Kapur K, Eugenicos M, Akbar A, Trudgill N, Houghton L, Dinning PG, Ford AC, Aziz Q, Spiler R, Trials 2019; 20-517-529.
 
Pathophysiology and Management of Diabetic Gastro-Enteropathy, Meldgaard T, Keller J, Olesen AE, Olesen SS, Krogh K, Borre M, Farmer AD, Brock B, Brock C, Drewes AM, Therapeutic Advances in Gastroenterology 2019, 17;12:1756284819852047.
 
Diabetic Gastroparesis – Perspectives from a Patient and Healthcare Providers Farmer AD, Bruckner Holt CE, Sadler E, Schwartz S, Kadirkamanthan S, Journal of Patient Centered Reviews 2019, 6(2):148-157.
 
Pathophysiology and Management of Opioid-Induced Constipation: European Expert Consensus Statement, Farmer AD, Drewes AM, Chiarioni G, De Giorgio R, O’Brien T, Morlion B, Tack J, UEJ Journal 2019, 7(1):7-20.
 
Linaclotide increases caecal pH, accelerates colonic transit and increases colonic motility in irritable bowel syndrome with constipation Farmer AD, Ruffle J, Hobson AR, Neurogastroenterology and Motility 2019, doi: 10.1111/nmo.13492.
 
Artificial intelligence assisted gastroenterology – promises and pitfalls, Ruffle J, Farmer AD, Aziz Q, American Journal of Gastroenterology 2019, 114(3):422-428.
 
Attitudes to out of programme experiences, research and academic training of gastroenterology trainees between 2007 and 2016, McFarlane M, Bhala N, China L, Alrubaiy L, Chedgy F, Disney BR, Farmer AD, Fogden E, Sadler GJ, Hull MA, McLaughlin J, Ellison H, Solomon J, Brookes MJ, Frontline Gastroenterology 2019, 10(1):57-66.
 
Diabetic enteropathy: From molecule to mechanism-based treatment, Meldgaard T, Olesen SS, Farmer AD, Krogh K, Wendel AA, Brock B, Drewes AM, Brock C, Journal of Diabetes Research 2018, doi: 10.1155/2018/3827301.
 
Preliminary report: parasympathetic tone links to functional brain networks during the anticipation and experience of visceral pain, Ruffle JR, Coen SJ, Giampietro V, Williams SC, Aziz Q, Farmer AD, Scientific Reports 2018, 8(1):13410.
 
Systematic Review and Meta-Analysis: Conditioned Pain Modulation in Irritable Bowel Syndrome, Albusoda A, Friss KA, Gysan MR, Ruffle JK, Drewes AM, Aziz Q, Farmer AD, Alimentary Pharmacology and Therapeutics 2018, 48(8):797-80.
 
UK clinical experience up to 52 weeks with linaclotide for irritable bowel syndrome with constipation, Yiannakou Y, Agrawal A, Allen PB, Arebi N, Brown S, Eugenicos M, Farmer AD, McLain-Smith S, McLaughlin J, Sander DS, Lawrance D, Emmanuel A, Therapeutic Advances in Gastroenterology 2018, 3;11:1756284818798791.
 
Regional gastrointestinal pH profile is altered in patients with type 1 diabetes and peripheral neuropathy, Wegeberg AM, Brock C, Brock B, Farmer AD, Hobson AR, Semler JR, Scott SM, Neurogastroenterology and Motility 2018, 30(11):e13407..
 
Pathophysiology, Diagnosis and Management of Chronic Intestinal Pseudo-obstruction, Downes T, Cheruvu MS, Karunaratne TB, De Giorgio R, Farmer AD, Journal of Clinical Gastroenterology 2018, 52(6):477-489.
 
Opioid Induced Constipation – Pathophysiology, Diagnosis and Management, Farmer AD, Downes TM, Bruckner-Holt CE, Ruggerio E, Del Vacchio S, De Giorgio R, Lancet Gastroenterology and Hepatology 2018, 3(3):203-212.
 
Morphology of subcortical brain nuclei is associated with autonomic function in healthy humans, Ruffle JK, Coen SJ, Giampietro V, Williams CR, Apkarian V, Farmer AD*, Aziz Q*, Human Brain Mapping 2018, 39(1):381-392, *joint senior authors.
 
Regional gastrointestinal contractility parameters using the wireless motility capsule: inter-observer reproducibility and influence of age, gender and study country, Farmer AD, Wegeberg AM L, Brock B, Hobson AR, Mohammed SD, Scott SM, Bruckner-Holt CE, Semler JR, Hasler WL, Hellström PM, Drewes AM, Brock B, Alimentary Pharmacology and Therapeutics 2018, 2018, 47(3):391-4.
 
Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in type 1 diabetes mellitus, Brock C, Jessen N, Brock B, Jakobsen PE, Hansen TK, Rantanen JM, Riahi S, Dimitrova YK, Dons-Jensen A, Aziz Q, Drewes AM, Farmer AD, Diabetes Medicine 2017, 34(10):1428-1434.
 
Acute physiological and electrical accentuation of vagal tone has no effect on pain or gastrointestinal motility in chronic pancreatitis, Juel J, Brock C, Olesen SS, Madzak A, Farmer AD, Aziz Q, Frøkjær JB, Drewes AM, Journal of Pain Research 2017, 31;10:1347-1355.
 
Vagal Influences in Rheumatoid Arthritis, Rasmussen SE, Pfeiffer MJ, Drewes AM, Farmer AD, Deleuran B, Stengaard K, Brock B, Brock C, Scandinavian Journal of Rheumatology 2017, 2:1-11. doi: 10.1080/03009742.2017.1314001.
 
Type 1 diabetic patients with peripheral neuropathy have pan-enteric prolongation of gastrointestinal transit times and an altered cecal pH profile, Farmer AD, Pedersen AG, Brock B, Jakobsen PE, Karmisholt J, Mohammed SD, Scott SM, Drewes AM, Brock C, Diabetologia 2017, 60(4):709-718.
 
Ehlers-Danlos syndrome Hypermobility type and its relevance for the gastroenterologist, Beckers B, Keszthelyi D, Fikree A, Vork L, Masclee A, Farmer AD, Aziz Q, Neurogastroenterology and Motility 2017, 29(8). doi: 10.1111/nmo.13013.
 
Narcotic bowel syndrome, Farmer AD, Gallagher J, Bruckner-Holt C, Aziz Q, Lancet Gastroenterology and Hepatology 2017, 2(5):361-368.
 
Transcutaneous cervical vagal nerve stimulation modulates cardiac vagal tone and tumor necrosis factor-alpha, Brock C, Brock C, Aziz Q, Møller HJ, Jensen MP, Drewes AM, Farmer AD, Neurogastroenterology and Motility 2017, 9(5). doi: 10.1111/nmo.12999.
 
The effects of eosinophilic on quality of life in a UK population – A Case Control Study, Hewett R, Alexakis C, Farmer AD, Ainley J, Chhaya V, Hayat J, Poullis A, Kang JY, Digestive Diseases and Sciences 2017, 30(1):1-7.
 
Vagal nerve stimulation in clinical practice, Farmer AD, Albu-Soda A, Aziz Q, British Journal of Hospital Medicine 2016, 77(11):645-651.
 
Irritable bowel syndrome, Farmer AD, Ruffle JK, Trend in Men’s Health 2016.
 
The role of esophageal hypersensitivity in functional esophageal disorders, Farmer AD, Ruffle JK, Aziz Q, Journal of Clinical Gastroenterology 2016, 51(2):91-99.
 
Neurophysiology of the esophagus with reference to pain – an update, Brock, B, Drewes AM, Farmer AD, Annals of the New York Academy of Science 2016, 1380(1):78-90.
 
Assessment of the cardiovascular and gastrointestinal complications of diabetes, Brock C, Brock, B, Pedersen AG, Drewes AM, Jessen N, Farmer AD, World Journal of Diabetes 2016, 25;7(16):321-32.
 
Pharmacological and other treatment modalities for esophageal pain, Hoff DAL, Brock C, Farmer AD, Dickman R, Ruffle J, Shaker A, Drewes AM, Annals of the New York Academy of Science 2016, 1380(1):58-66.
 
Effect of fibre supplementation on chronic idiopathic constipation in adults: systematic review and meta-analysis of randomised controlled trials, Christodoulides S, Dimidi E, Fragkos KC, Farmer AD, Whelan K, Scott SM, Alimentary Pharmacology & Therapeutics 2016, 4(2):103-16.
 
Phenotyping of subjects for large scale studies on patients with IBS, Boeckxstaens GE, Drug V, Dumitrascu D, Farmer AD, Hammer J, Hausken T, Niesler B, Pohl D, Pojskic L, Polster A, Simren M, Stengel M, Van Oudenhove L, Vassallo M, Wensaas KA, Aziz Q, Houghton LA, Neurogastroenterology and Motility 2016, 28(8):1134-47.
 
Provocative testing of the esophagus and its future, Farmer AD, Franchina M, Gregersen H, Penagini R, Shaker, A, Soffer E, Annals of the New York Academy of Science 2016, 1380(1):33-47.
 
Irritable Bowel Syndrome, Enck P, Aziz Q, Giovanni B, Farmer A, Fukudo S, Mayer E, Niessler B, Quigley E, Radijic-Stojanovic M, Schemann M, Schwille-Kiuntke J, Simren M, Zipfel S, Spiller RC, Nature Reviews Disease Primers 2016, 24;2:16014.
 
Management of Chronic Visceral Pain, Olesen AD, Olesen SS, Farmer AD, Aziz Q, Drewes AM, Pain Management 2016, 6(5):469-86.
 
Modulation of Vagal Tone Enhances Gastro-Duodenal Motility and Reduces Somatic Pain Sensitivity, Frøkjær JB, Bergmann S, Brock C, Madzak A, Farmer AD, Ellrich J, Drewes AM, Neurogastroenterology and Motility 2016;28(4):592-8.
 
Understanding the sensory irregularities of esophageal disease, Farmer AD, Brock C, Frokjaer JB, Gregersen H, Khan S, Lelic D, Lottrup C, Drewes AM, Experts Reviews Gastroenterology and Hepatology 2016, 10(8):907-14.
 
Brain changes in diabetes mellitus patients with gastrointestinal symptoms, Drewes AM, Søfteland E, Dimcevski G, Farmer AD, Brock C, Frøkjær JB, Krogh K, Drewes AM, World Journal of Diabetes 2015, 7(2):14-26.
 
Cannabinoid hyperemesis syndrome – an important differential diagnosis of persistent unexplained vomiting, Ruffle JK, Bajgoric S, Samra K, Chandrapalan S, Aziz Q, Farmer AD, European Journal of Gastroenterology and Hepatology 2015, 27(12):1403-8.
 
The effects of camicinal, a novel motilin agonist, on gastro-oesophageal function in healthy humans – a randomised placebo controlled trial, Hobson AR, Farmer AD, Dewit OE, O’Donnell M, Hacquoil K, Robertson D, Barton ME, Dukes GE, Neurogastroenterology and Motility 2015, 27(11):1629-37.
 
Regional gastrointestinal transit and pH studied in 215 healthy volunteers using the wireless motility capsule: influence of age, gender, study country and testing protocol, Wang YT, Mohammed SD, Farmer AD, Wang D, Zarate N, Hobson AR, Hellström PR, Semler JR, Kuo B, Rao SS, Hasler WL, Camilleri M, Scott SM, Alimentary Pharmacology and Therapeutics 2015, 42(6):761-72.
 
Irritable Bowel Syndrome, Farmer AD, Ruffle JK, Hamdan Medical Journal 2015, 8 (3): 265-278.
 
Systematic Review with Meta-analysis: Prevalence of Bile Acid Malabsorption in Irritable Bowel Syndrome with Diarrhoea, Slattery SA, Niaz O, Aziz Q, Ford AC, Farmer AD, Alimentary Pharmacology and Therapeutics 2015, 42(1):3-11.
 
Visually induced nausea causes characteristic changes in cerebral, autonomic and endocrine function in humans, Farmer AD, Ban VF, Coen SJ, Sanger GJ, Barker GJ, Giampietro V, Williams SC, Gresty M, Webb DL, Hellstrom P, Andrews PLR, Aziz Q, Journal of Physiology 2015, 593(5): 1183-1196.
 
Preliminary report - modulation of parasympathetic nervous system tone influences oesophageal pain hypersensitivity, Botha C* & Farmer AD*, Nilsson M, Brock C, Gavrila AD, Drewes AM, Knowles CH, Aziz Q, Gut 2014, 64: 611-7. * Joint first authors.
 
Oesophageal and gastric function, Farmer AD, Hobson AR, Aziz Q, Medicine 2015, 43 (5): 262–265.
 
The influence of extraversion on brain activity at baseline and during the experience and expectation of visceral pain, Ruffle JK, Farmer AD, Kano M, Giampietro V, Aziz Q, Coen SJ, Personality and Individual Difference 2015, 7: 248-2535.
 
The Neurophysiology of the Esophagus, Drewes AM, Brokjær A, Lottrup C, Gregersen H, Farmer AD, Frøkjær JB, Brock C, Annals of the New York Academy of Science 2014, 1325(1):57-6.
 
The Pharmacology of the Esophagus, Drewes AM, Krarup AL, Olesen AE, Farmer AD, Blackshaw LA, Bordin DS, Masharova AA, Moawad FJ, Brock C, Lottrup C, Brokjaer A, Annals of the New York Academy of Science 2014, 1325(1):23-39.
 
Normal Values and Reproducibility of the Real Time Index of Vagal Tone in Healthy Humans – A Multi-Centre Study, Farmer AD, Coen SJ, Kano M, Weltens N, Botha C, Paine PA, Van Oudenhove L, Aziz Q, Annals of Gastroenterology, 2014, 27:362-368x.
 
Mechanisms and management of functional abdominal pain, Farmer AD, Aziz Q, Journal of the Royal Society of Medicine 2014, 107(9):347-354.
 
The role of the parasympathetic nervous system in visually induced motion sickness: systematic review and meta-analysis, Farmer AD, Al-Omran Y, Aziz Q, Andrews PL, Experimental Brain Research 2014, 232(8):2665-73.
 
How the gut affects the state of mind – implications for mood disorders, Farmer AD, Randall HR, Aziz Q, Journal of Physiology 2014, 592:2981-8.
 
Prospective evaluation of undiagnosed joint hypermobility syndrome in patients with gastrointestinal symptoms, Fikree A, Ahktar R, Farmer AD, Morris J, Knowles CH, Grahame R, Aziz Q, Clinical Gastroenterology and Hepatology 2014, S1542-3565.
 
Mechanisms of Visceral Pain in Health and Disease, Farmer AD, Aziz Q, Scandinavian Journal of Pain 2014, 5(2): 51-60.
 
Caecal pH is a biomarker of excessive fermentation in patients with bloating and distension, Farmer AD, Scott SM, Dukes G, Mohammed S, Hobson AR, World Journal of Gastroenterology 2014, 20(17): 5000-7.
 
Psychophysiological Responses to Visceral and Somatic Pain in Functional Chest Pain Identify Clinically Relevant Pain Clusters, Farmer AD, Kano M, Coen SJ, Naqvi H, Knowles CH, Furlong PL, Lightman S, Aziz Q, Neurogastroenterology & Motility 2014, 26 (1):139-4.
 
Gastrointestinal Motility Revisited – The Wireless Motility Capsule, Farmer AD, Scott SM, Hobson AR, United European Gastroenterology Journal 2013, 1 (6): 413-421.
 
The Neurophysiology of the Esophagus, Woodland P, Sifrim D, Krarup AL, Brock C, Frøkjaer JB, Lottrup C, Drewes AM, Swanstrom LL, Farmer AD, Annals of the New York Academy of Science 2013, 1300 (1): 53-70.
 
Psychological Traits Influence Autonomic Nervous System Recovery Following Esophageal Intubation in Health and Functional Chest Pain, Farmer AD, Kano M, Coen SJ, Naqvi H, Aziz Q, Neurogastroenterology & Motility 2013, 25(12):950-e772.
 
Physiological and psychological individual differences influence resting brain function measured by ASL perfusion, Kano M, Coen SJ, Farmer AD, Aziz Q, Williams SCR, Alsop DC, Fukudo S, O’Gorman RL, Brain Structure & Function 2013, 219: 1673-1684.
 
Psychophysiological Responses to Pain Identify Reproducible Human Clusters, Farmer AD, Coen SJ, Kano M, Paine PA, Shwahdi M, Jafari J, Kishor J, Worthen SF, Rossiter H, Kumari V, Williams SCR, Brammer M, Giampietro VP, Droney J, Riley J, Furlong PL, Knowles CH, Lightman SL, Aziz Q, Pain 2013, 154(11): 2266-76.
 
Functional Abdominal Pain: Clinical Update, Farmer AD, Aziz Q, Pain: Clinical Updates 2013.
 
Sex differences in brain response to anticipated and experienced visceral pain in healthy subjects, Kano M, Farmer AD, Aziz Q, Giampietro VP, Brammer MJ, Williams SC, Fukudo S, Coen SJ, American Journal of Physiology: Gastrointestinal & Liver Physiology 2013, 304(8): G687-99.
 
Gut Pain, Farmer AD, Aziz Q, British Journal of Pain 2013, 7(1): 39-47.
 
Opioids and the Gastrointestinal Tract – Narcotic Bowel Syndrome & Literature Review, Farmer AD, Ferdinand E, Aziz Q, Journal of Neurogastroenterology and Motility 2013, 19(1): 94-8.
 
The Management of Chronic Constipation, Farmer AD, Independent Nurse 2012.
 
Diabetic Gastroparesis: pathophysiology, evaluation and management, Farmer AD, Kadirkamanathan SS, Aziz Q, British Journal of Hospital Medicine 2012; 73(8): 451-6.
 
Mood Disorders in Inflammatory Bowel Disease: Relations to Diagnosis, Disease Activity, Perceived Stress and Other Factors, Goodhand JR, Wahed M, Farmer AD, Mawdsely J, Aziz Q, Rampton DS, Inflammatory Bowel Disease 2012, 18(12): 2301-9.
 
Neuroticism Influences Brain Activity During the Experience of Visceral Pain, Coen SJ, Kano M, Farmer AD, Kumari V, Giampietro V, Brammer M, Williams SC, Aziz Q, Gastroenterology 2011; 141(3): 909-91.
 
Mechanism-based evaluation and treatment of esophageal disorders, Gregersen H, Drewes AM, Frøkjaer JB, Krarup AL, Lottrup C, Farmer AD, Aziz Q, Hobson AR, Annals of the New York Academy of Science 2011; 1232: 341-8.
 
Drug Induced Liver Injury, Farmer AD, Brind AM, Medicine 2011; 39 (9): 536-540.
 
Pain Associated with Chronic Narcotic Dependence, Farmer AD, Aziz Q, European Gastroenterology and Hepatology Review 2011.
 
Why a PhD/MD Enhances Gastroenterological Training, Farmer AD, Aziz Q, Frontline Gastroenterology 2010; 1(3): 182-186.
 
Joint Hypermobility and Rectal Evacuatory Dysfunction: an aetiological link in abnormal connective tissue? Mohammed S, Zarate N, Farmer AD, Grahame R, Luniss P, Aziz Q, Knowles CH, Scott SM, Neurogastroenterology & Motility 2010; 22 (10): 2085-e283.
 
A Novel In Vivo Skin Extensibility Test for Joint Hypermobility, Farmer AD, Douthwaite H, Gardiner S, Aziz Q, Grahame R, J Rheumatology 2010; 37(7): 1513-18.
 
The Future of Neuroscientific Research in Functional Gastrointestinal Disorders: Towards an Integrative, Multidimensional Visceral Pain Endophenotype? Farmer AD, Tack J, Aziz Q, Van Oudenhove L, Journal of Psychosomatic Research 2010; 68 (5): 1351-1356.
 
Unexplained Gastrointestinal Symptoms and Joint Hypermobility – Is Connective Tissue the Missing Link? Zarate N & Farmer AD*, Mohammed S, Scott SM, Knowles CH, Grahame R, Aziz Q, Neurogastroenterology and Motility 2010; 22(3): 252-278, *Joint first authors.
 
Social Networking Sites – A Novel Portal for Communication, Farmer AD, Bruckner Holt CEM, Cook MJ, Hearing SD, Postgraduate Medical Journal 2009; 85(1009): 455-459.
 
Visceral Pain Hypersensitivity, Farmer AD, Aziz Q, British Medical Bulletin 2009; 91:123-136.
 
Portal Vein Thrombosis in the District General Hospital: Management and Outcomes, Farmer AD, Saadeddin A, Bruckner-Holt CEM, Bateman JM, Ahmed M, Syn WK, European Journal of Gastroenterology and Hepatology 2009; 21(5): 517-521.
 
Recent Advances in Chronic Visceral Pain, Farmer AD, Aziz Q, Current Opinions in Supportive and Palliative Care 2008; 2(2): 116-21.
 
Liver Biopsy in the District General Hospital: Changes Over Two Decades, Syn WK, Bruckner-Holt CEM, Farmer AD, Howdle S, Bateman JM, World Journal of Gastroenterology 2007; 13(40): 5336-42.

Honors and Awards

  • University Hospitals of North Midlands NHS Trust Chief Executive Officer Award (Best clinician award); 2019
  • United European Gastroenterology Federation Rising Star Award (Top European gastroenterology award); 2018
  • F1000 Faculty Member Award for Gastroenterology & Hepatology (International teaching award); 2017
  • UHNM Clinical Excellence Award; 2016-2024
  • British Society of Gastroenterology Neurogastroenterology and Motility Section Best Abstract Award; 2016
  • Gastroparesis and Intestinal Failure Trust Research Award (Best clinical care award); 2014
  • ANMS Clinical Distinguished Presentation Prize; 2012
  • Almirall Research Prize for Functional GI Disorders (Best international clinical research); 2011
  • ANMS Research Award (Best international clinical research); 2010
  • Stephen Whittaker Research Prize, West Midlands Physicians’ Association (regional best research); 2010
  • Institute of Cell & Molecular Science Research Prize Barts & The London School of Medicine (best research); 2010
  • Midlands Gastroenterological Society Research Prize; 2007
  • First Prize in Anatomical Dissection, University College London; 1997

Professional Organizations and Associations

  • British Society of Gastroenterology (BSG)
  • United European Gastroenterology Federation (UEG)
  • European Society of Neurogastroenterology & Motility (ESNM)
  • Rome Foundation
  • American Neurogastroenterology and Motility Society (ANMS)
  • International Association for the Study of Pain (IASP)
  • Royal College of Physicians (London)
  • Royal Society of Medicine (London)
  • The Pelvic Floor Society (London)