Ranjit Ray, Ph.D.

Professor, Division of Infectious Diseases and Immunology
Department of Internal Medicine

Courses Taught

Virology, viral immunology

Education

Ph.D., M.Sc.

Research Interests

Virology
Immunology

Labs and Facilities

Ray's team worked on various aspects of respiratory and hepatitis viruses for more than 30 years. Currently, the team is focusing primarily on hepatitis C virus (HCV) as a major area of research.

Ray's laboratory is a 1600-square-foot, BSL-2 facility available for the use on the 8th floor of Edward A. Doisy Research Center on the Saint Louis University School of Medicine campus. The laboratory has gas, vacuum, one chemical hood, 3Class II biosafety cabinets, CO2 incubators, water baths, refrigerators, two -850C freezers, microfuges, refrigerated centrifuge, tissue culture centrifuges, UV transilluminator, speed vac, electrophoresis power supplies, gel dryer with vacuum pump, bacteria culture shakers, electroporator, PCR thermocyclers, 7500 Fast real-time PCR, Strata linker, Nikon TM inverted tissue culture microscopes. A shared instrument facility near PI’s laboratory is also available. The lab has four PC desktop computers, all connected with University network and internet access.

Publications and Media Placements

Ranjit Ray Bibliography

Haga Y, Bandyopadhyay D, Khatun M, Tran E, Steele R, Banerjee S, Ray R, Nazzal M, Ray RB, Increased expression of long non-coding RNA FIRRE promotes hepatocellular carcinoma by HuR-CyclinD1 axis signaling, Journal of Biological Chemistry (2024), doi: https://doi.org/10.1016/j.jbc.2024.107247.

Yuki Haga, Ranjit Ray, Ratna B. Ray. Silmitasertib in combination with cabozantinib impairs liver cancer cell cycle progression, induces apoptosis and delays tumor growth in a preclinical model. Mol Carcinogenesis. 2024 Oct 8. doi: 10.1002/mc.23827. Epub ahead of print. PMID: 39377735.

Yuki Haga, Sydney Coates, Ranjit Ray. Hepatitis C virus chronicity and oncogenic potential: vaccine development progress. Invited Review Article - “Vaccines for Cancer Prevention”. Angelo Azzi, Editor-in-Chief. Molecular Aspects of Medicine, Elsevier, 99,101305, 2024. PMID: 39167987.

Yuki Haga, Preedia Babu E, Marzena Swiderska-Syn, Erin K. Reagan, Drew Weissman, and Ranjit Ray. Hepatitis C virus modified SE2F442NYT-mRNA-LNP candidate vaccine promotes helper CXCR5+T cells. J. Virology, October 2025 Volume 99 Issue 10 e01355-25. https://doi.org/10.1128/jvi.01355-25

Honors and Awards

Naomi Judd Award from Friends of the Saint Louis University Liver Center (2012)

Professional Organizations and Associations

Membership

American Society for Virology
American Society for Microbiology
American Association of Immunologists
Editorial Board, Virus Research
Editorial Board, Journal of Virology
Editorial Board, Scientific Reports (until 2023)
Academic Editor, PLoS ONE (until 2018)
Editorial Board, Cells
Guset Editor, mBio
Liver Center, Saint Louis University
Cancer Center, Saint Louis University
Siteman Cancer Center, Washington University School of Medicine

Journal Review

Advances in Virology
American Journal of Pathology
American Journal of Transplantation
Blood
Cancer Letters
Cell Death & Disease
Cellular and Molecular Life Sciences, Birkhauser, Basel
European Journal of Biochemistry
eBioMedicine
FASEB Journal
Gastroenterology
Gene
Hepatology
Journal of Clinical Investigation
Journal of General Virology
Journal of Hepatology
Journal of Infectious Diseases
Journal of Immunology
Journal of Medical Virology
Journal of the National Cancer Institute
Journal of Virology
mBio
Molecular & Cellular Biology
Molecular Therapy
Nature Communications
Nature Medicine
Nature Cell Biology
PLoS Pathogens
PLoS One
Proceedings of the National Academy of Sciences, U.S.A.
Science Advances
Vaccine
Virology
Virus Research

Funding Agency Review

Medical Research Council of Canada
Swiss National Research Programme
National Institutes of Health
The Wellcome Trust
The WHO Programme for Vaccine Development
Veterans Affairs Medical Research Service