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T. Scott Isbell, Ph.D., DABCC, FAACC

Associate Professor

Director, Clinical Chemistry; Director, Point of Care Testing

Clinical Pathology, Laboratory Medicine


Ph.D., University of Alabama at Birmingham, 2007


American Board of Clinical Chemistry

Research Interests

Development of personalized laboratory diagnostics using machine learning and predictive analytics


PubMed Listing

Xin Sha, T. Scott Isbell, Rakesh P. Patel, Cynthia S. Day, and S. Bruce King. Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO). Journal of the American Chemical Society. 2006; 128 (30): 9687-92.

Jeffrey R. Koenitzer, T. Scott Isbell, Hetal D. Patel, Gloria A. Benavides, Dale A. Dickinson, Rakesh P. Patel, Victor M. Darley-Usmar, Jack R. Lancaster, Jr. Jeannette E. Doeller, David W. Kraus. Hydrogen Sulfide Mediates Vasoactivity in an Oxygen Dependent Manner. American Journal of Physiology-Heart and Circulatory Physiology. 2007 Apr; 292(4):H1953-60.

John D Lang Jr, Xinjun Teng, Philip Chumley, Jack H Crawford, T. Scott Isbell, Balu K Chacko, Yuliang Liu, Nirag Jhala, Ralph Crowe, Alvin B Smith, Richard C Cross, Luc Frenette,  Eric Kelley,, Diana W Wilhite, Cheryl R Hall, Grier P Page, J Steven Bynon, Devin E Eckhoff and Rakesh P. Patel. Preemptive Administration of Inhaled Nitric Oxide Accelerates Restoration of Liver Function in Adults Following Orthotopic Liver Transplantation. Journal of Clinical Investigation. 2007 Sep; 117(9):2583-91.

T. Scott Isbell, Mark T. Gladwin and Rakesh P. Patel. Hemoglobin Oxygen Fractional Saturation Regulates Nitrite-Dependent Vasodilation of Aortic Ring Bioassays. American Journal of Physiology-Heart and Circulatory Physiology. 2007 Oct;293(4):H2565-72

Gloria A. Benavides, Giuseppe L. Squadrito, Robert W. Mills, Hetal D. Patel, T. Scott Isbell, Rakesh P. Patel, Victor M. Darley-Usmar, Jeannette E. Doeller, David W. Kraus. Hydrogen Sulfide Mediates the Vasoactivity of Garlic. Proceedings of the National Academy of Sciences. 2007 Nov 13; 104 (46): 17977-82.

T. Scott Isbell, Chiao-Wang Sun, Li-Chen Wu, Xinjun Teng, Dario A. Vitturi, Billy G Branch, Christopher G Kevil, Namasivayam Ambalavanan, Lisa Schwiebert, Jinxiang Ren, Kevin M. Pawlik, Matthew B. Renfrow, Rakesh P. Patel, Tim M. Townes. Role of SNO-Hemoglobin in Normal Development and Physiology. Nature Medicine. 2008 July. 14(7): 773-7.

Teng X, Scott Isbell T, Crawford JH, Bosworth CA, Giles GI, Koenitzer JR, Lancaster JR, Doeller JE, W Kraus D, P Patel R. Novel method for measuring S-nitrosothiols using hydrogen sulfide. Methods Enzymology. 2008; 441:161-72.

T. Scott Isbell and Reina Villareal-Amarmento. A Case of Thick but Brittle Bones and Instant Tea. Clinical Chemistry. 2010. 56 (6): 1041-44.

ME Shoman, JF DuMond, TS Isbell, JH Crawford, A Brandon, J Honovar, DA Vitturi, CR White, RP Patel, SB King. Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties. J Med Chem. 2011 Feb 24;54(4):1059-70.

TS Isbell and ME Lyon. Glucose meters: Where are we now? Where are we heading? Medical Laboratory Observer. 2012. Jun; 44(6): 16-18.

Book Chapters

T. Scott Isbell, Emily Jungheim, and Ann M Gronowski. Reproductive Related Disorders. In: Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th Edition. Eds., Burtis C, Bruns D, and Ashwood E. Elsevier Press. St Louis MO. 2012

Honors and Awards

AACC Outstanding Speaker Award, 2011
Paul E. Strandjord Young Investigator Award from the Academy of Clinical Laboratory Physicians and Scientists, 2010
Richard Marshall Education Award from the Midwest section of AACC, 2010
Past-Presidents' Scholarship Award from the American Association for Clinical Chemistry's Van Slyke Foundation, 2008-2010

Professional Organizations and Associations

AACC Academy, Fellow
American Society for Clinical Pathology
American Association for Clinical Chemistry