Sarah Riley, Ph.D., DABCC, FACB
Associate Professor
Pathology
Director
Forensic Toxicology Laboratory
Education
Ph. D., Saint Louis University, 2009
Certifications
American Board of Toxicological Chemistry--Board Eligible--2014
American Board of Clinical Chemistry--Diplomate--2012
Research Interests
Clinical toxicology, forensic toxicology, clinical mass spectrometry, global health, laboratory outreach
Publications
DeMarco, ML, Dietzen, DJ, Brown, SM. Sweating the small stuff: adequacy and accuracy in sweat chloride determination. Clin Biochem. 2015;48(6):443-448. doi:10.1016/j.clnbiochem.2014.12.011 PMID:25530017
Li F, Guo CJ, Huang CC, Yu G, Brown SM, Xu S, Liu Q. Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice. Anesthesiology. 2015;122(4):768-75. doi:10.1097/ALN.0000000000000607 PMID:25646842
Mitsios JV, McClellan A, Brown S, Gronowski AM. Human chorionic gonadotropin and α-fetoprotein in cerebral spinal fluid: method validation and retrospective review. Clin Biochem. 2014;47(7-8):632-5. doi:10.1016/j.clinbiochem.2014.01.008 PMID:24462967
Brown SM, Campbell SD, Crafford A, Regina KJ, Holtzman MJ, Kharasch ED. P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception. J Pharmacol Exp Ther. 2012;343(1):53-61. doi:10.1124/jpet.112.193433 PMCID:PMC3464040 PMID:22739506
Brown SM, Holtzman M, Kim T, Kharasch ED. Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active. Anesthesiology. 2011;115(6):1251-60. doi:10.1097/ALN.0b013e318238fea0 PMCID:PMC3560935 PMID:22037640
Fan J, Brown SM, Tu Z, Kharasch ED. Chemical and enzyme-assisted syntheses of norbuprenorphine-3-β-D-glucuronide. Bioconjug Chem. 2011;22(4):752-8. doi:10.1021/bc100550u PMCID:PMC3091394 PMID:21434652
Dallas J, Brown SM, Hock K, Scott MG, Skrupky LP, Boyle WA 3rd, Kollef MH. Diagnostic utility of plasma procalcitonin for nosocomial pneumonia in the intensive care unit setting. Respir Care. 2011;56(4):412-9. doi:10.4187/respcare.00979 PMID:21255510
Brown SM, Upadhya R, Shoemaker JD, Lodge JK. Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase. Eukaryot Cell. 2010;9(6):971-80. doi:10.1128/EC.00271-09 PMCID:PMC2901651 PMID:20400467
Brown SM, Smith DM, Alt N, Thorpe SR, Baynes JW. Tissue-specific variation in glycation of proteins in diabetes: evidence for a functional role of amadoriase enzymes. Ann N Y Acad Sci. 2005;1043:817-23. doi:10.1196/annals.1333.094 PMID:16037309
Honors and Awards
The Association for Mass Spectrometry: Applications for the Clinical 2015
Laboratory, Laboratory Director Travel Grant (competitive application)
Fellow of the National Academy of Clinical Biochemistry 2013
American Association of Clinical Chemistry Outstanding Speaker Award 2012
Early Career Women Faculty in Medicine and Science Leadership Seminar 2012
(competitive application)
Paul E. Strandjord Young Investigator Award, With Distinction 2011
Academy of Clinical Laboratory Physicians and Scientists
Professional Organizations and Associations
American Association of Clinical Chemistry
National Academy of Clinical Biochemistry Academy of Clinical Laboratory Physicians
and Scientists