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Michael Smiley, M.D.

Professor, Division of Pediatric Pulmonology; Associate program director, Pediatric Residency Program; Director, Cystic Fibrosis Program
Department of Pediatrics

Courses Taught

M2 Pre-clerkship Pulmonary Medicine; M4 Pulmonary Elective Clerkship Director

Education

Fellowship
Nationwide Children's Hospital, The Ohio State University (2016)

Residency
Naval Medical Center Portsmouth (2011)

Medical School
Saint Louis University School of Medicine (2005)

B.S., Zoology
University of Wisconsin - Madison (2001)

Practice Areas

After earning his medical degree, Michael Smiley, M.D., went on to a diverse career in the United States Navy. It was during a deployment as a Naval Flight Surgeon that a 26-year-old enlisted Aircrew presented with hemoptysis and was ultimately diagnosed with cystic fibrosis; thus, Smiley’s interest in CF began. Smiley completed his Flight Surgery tour at the Naval Air Station in Brunswick, Maine; pediatric residency at The Naval Medical Center in Portsmouth, VA; a tour as a general pediatrician at the U.S. Naval Hospital in Rota, Spain; and fellowship in pediatric pulmonary medicine at Nationwide Children’s Ohio. From 2016-2019 he was stationed in San Diego at the Naval Medical Center serving as Cystic Fibrosis Affiliate Center Director and Director of Pediatric Subspecialties. During his time in San Diego, he created a much-needed transition program for military dependents with CF.

In 2019, Smiley left Active Duty service and joined SSM Health Cardinal Glennon Children’s Hospital. His primary interests relate to quality improvement in CF transition and CF newborn screening.  He has developed a clinical interest in genotype-phenotype correlation and the diversity of CF phenotypes, enhanced by his involvement with the CRMS/CFSPID Guidelines Committee from 2021-2023.  In his abundance of spare time, he participates in the Air Force Reserves as a pediatrician assigned to a humanitarian and disaster relief platform with the 932nd Medical Group at Scott Air Force Base.

Specialties

  • Cystic fibrosis
  • CFTR-related metabolic syndrome (CRMS/CFSPID)
  • Severe pediatric asthma
  • Neuromuscular respiratory weakness
  • Tracheostomy and ventilator-dependent children
  • Complex Medical Care Program
  • Congenital lung malformations
  • Chronic cough
  • Functional respiratory disorders

Publications and Media Placements

Green DM, Lahiri T, Raraigh KS, Ruiz F, Spano J, Antos N, Bonitz L, Christon L, Gregoire-Bottex M, Hale JE, Langfelder-Schwind E, Perez A, Maguiness K, Massie J, McElroy-Barker E, McGarry ME, Mercier A, Munck A, Oliver KE, Self S, Singh K, MPH, MS, Smiley M, Snodgrass S, Tluczek A, Tuley P, Lomas P, Wong E, Hempstead SE, Faro A, Ren CL, MD. "Cystic Fibrosis Foundation Evidence-Based Guideline for the Management of CRMS/CFSPID." Pediatrics. 2024;153(5): e2023064657. PMID: 38577740

Smiley M, Sicignano N, Rush T, Lee R, Allen E. "Outcomes of Follow-Up Care After an Emergency Department Visit Among Pediatric Asthmatics in the Military Health System." J Asthma. 2016 Aug:53(8): 816-824. PMID: 27115719

Robinson M, Smiley M, Kotha K, Udoji T. "Plastic Bronchitis Treated With Topical-Type Plasminogen Activator and Cryotherapy." Clinical Pediatrics. 2016 Oct: 55(12): 1171-1175

The Glennon Factor Podcast: Discussion of Complex Medical Child Program (2024)

KMOV Channel 4 Series: The Science of Healing: Cystic Fibrosis (2021)

KMOV Channel 4 Evening News: Respiratory Infections in Children (2020)

KTVI Channel 2 Morning News: The Risks of Vaping (2019)

Honors and Awards

  • Top Teacher Award in Pediatric Subspecialty (2023, 2024, 2025)
  • Ursula Rolfe Award (2023)
  • St. Louis Top Doctors (2022, 2023, 2024, 2025)
  • Associate Master Clinician Award at Naval Medical Center San Diego (2018)
  • Fran C. Rash Teacher of the Year Award (2018)
  • Outstanding Fellow of the Year (2015)
  • U.S. Naval Hospital Rota Spain Clinician of the Year (2013)

Professional Organizations and Associations

  • American Thoracic Society
  • American Academy of Pediatrics
  • Association of Pediatric Program Directors

Community Work and Service

  • Chief of Medical Services at 932 MDS in Air Force Reserves
  • Cystic Fibrosis Foundation Gateway Chapter Board Member