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Division of Gastroenterology and Hepatology

The Saint Louis University Division of Gastroenterology and Hepatology has a long history of excellence in clinical care, education and research.

Our division has the SLU Liver Center, a Center for Abdominal Transplant, a Gastrointestinal Motility Center and a Center for Pancreatic and Biliary Disorders. Our SLUCare Center for Pancreatic and Biliary Diseases is one of only 30 National Pancreas Foundation Centers, recognized for excellence in treating pancreatic diseases.

Our mission is to provide the best possible clinical care to our patients, an excellent education for our medical students, house staff, subspecialty residents and community physicians, and to continue to have expertise in clinical and basic research.

Our faculty are experts in their fields and are nationally and internationally recognized for their outstanding contributions to the practice of gastroenterology and hepatology. Our patient practice treats all forms of liver diseases including hepatitis, nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), hepatocellular carcinoma, liver transplantation (pre- and post-transplant) and hemochromatosis.

Advanced Endoscopists

Our advanced endoscopists treat patients with pancreatic, biliary and gallbladder disorders, and gastrointestinal malignancies. We use state-of-the-art equipment to do endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography (ERCP), and other advanced interventional and therapeutic endoscopic procedures.


Our gastroenterologists treat patients with gastrointestinal disorders such as inflammatory bowel disease, Crohn’s disease, abdominal pain, GERD, diverticulitis, diverticulosis, diarrhea, lactose intolerance, constipation, peptic ulcers and ulcerative colitis. They perform diagnostic procedures such as colonoscopy, endoscopy and sigmoidoscopy.

Research Unit

We have a large gastroenterology and hepatology research unit where many of our NIH and industry-sponsored studies are performed. The division has several state-of-the art laboratories for the research we perform.

Fellowship Program

The Division of Gastroenterology and Hepatology has an outstanding three-year fellowship program to train future gastroenterologists and hepatologists. Our fellows have historically had a 100 percent pass rate when they take their boards.

Learn more about our Fellowship Program

Endowed Chair in Gastroenterology

Prompted by the gratitude for the medical education he received at Saint Louis University School of Medicine and his pride in the division’s accomplishments, James F. King, M.D., funded the first endowed chair in gastroenterology at Saint Louis University School of Medicine.

The current chair is James F. King, M.D., professor of internal medicine and co-director of the Saint Louis University Liver Center.

Clinical Trials and Studies

The Division of Gastroenterology and Hepatology at Saint Louis University has led the nation in enrollment in several large, multicenter clinical trials, and is a recognized leader in both clinical and laboratory based research in liver disease. Clinical research in liver disease is conducted in the GI/Hepatology Studies Unit and the NIH Clinical Studies Unit on the second floor of the Saint Louis University Salus Center in the Center for Biomedical and Health Care Research.

GI/Hepatology Clinical Studies Unit

Our GI/Hepatology clinical studies unit sees more than 200 patients each month who are involved with ongoing industry sponsored research protocols. Currently, there are over 40 active clinical protocols with 15 new clinical trials pending site initiation. These pharmaceutical industry sponsored trials currently include the following areas of research:

  • Hepatitis C
  • Hepatitis B
  • Primary biliary cirrhosis
  • Primary sclerosing cholangitis
  • Liver cancer
  • Hepatorenal syndrome
  • Irritable bowel syndrome (IBS)
  • Barrett’s esophagus
  • Fatty liver disease  (NASH)
  • Liver transplantation

Ongoing clinical research activities allow patients to be included in protocols evaluating various new therapies for the treatment of liver diseases. Many patients can receive the latest forms of therapy at no charge with the support of a pharmaceutical industry sponsored study. The clinical studies unit staff includes full-time certified research nurse coordinators, data coordinators, regulatory staff, phlebotomists, an investigational product coordinator and a nurse manager.

For information regarding industry sponsored clinical trials, call the GI/Hepatology Clinical Studies Unit at 314-977-9400 to speak with a research coordinator.

NIH Clinical Studies Unit (NIH CSU)

The NIH Clinical Studies Unit provides space and services to support adult and pediatric research that is funded by federal or foundation support. Approximately 150 patients are seen in this unit each month. Current clinical studies conducted in this unit include the following areas of research:

  • Hepatitis B
  • Fatty liver disease (NASH)
  • Early detection of liver cancer
  • Pancreatitis
  • Primary biliary cirrhosis
  • Hepatitis C
  • Alpha-1 Antitrypsin deficiency

For information on government sponsored clinical trials, call the NIH Clinical Studies Unit at 314-977-9340 to speak with a research coordinator.