Healthy volunteers of all ages, races, and genders are needed to continue vaccine development at the Saint Louis University Center for Vaccine Development.
Participation in a vaccine study is voluntary and confidential. All study vaccines and tests are free of charge and volunteers receive compensation for time and travel.
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This study involves a procedure called Leukapheresis to collect large amounts of white blood cells that will be removed from your blood to study the immune response.
For more information about the study, please contact the Vaccine Center at 314-977-6333 or 1-866-410-6333 (toll-free) and refer to Study #320, IRB:27913.
Infection with a flu virus is a major public health threat, because it is able to spread rapidly through populations and affect large numbers of people. It is responsible for about 36,000 deaths each year in the U.S. Many deaths occur among older people. Current flu vaccines protect older people against flu, but not as well as desired. The new flu vaccine contains something called an “adjuvant”, which is something that is mixed with the normal flu vaccine before it is given to a patient. This adjuvant helps the body to have a better immune response to the vaccine, so it is more likely to stop you getting flu. If you participate in this second part of the study, you will receive either the adjuvanted vaccine dose picked in Part 1 or unadjuvanted high dose flu vaccine. The vaccine in this study has a new type of adjuvant; it is not yet approved for use by the Food and Drug Administration (FDA). The FDA approval process for the new flu vaccine starts with this study.
You will be compensated $75 per visit and $10 per phone call for participating.
There are about eight visits and about two phone calls over approximately 12 months as part of this study.
To discuss volunteering, please contact a nurse at 1-866-410-6333 (toll free) or at firstname.lastname@example.org and refer to study # 311B , IRB # 25821.