The Saint Louis University Department of Biochemistry and Molecular Biology maintains a number of facilities and resources for use by researchers.
Protein Core Facility
A shared-use facility that supports expression, purification and analysis of research proteins by providing an array of instrumentation and consultation on strategies for protein production from small to large scale. The facility is managed by Dave Wood, Ph.D. Contact him at 314-977-9220 or firstname.lastname@example.org.
Genomics Core Facility
This full-service facility provides investigators with a variety of options for whole genome analysis via microarrays, high-throughput screening, immunoprecipitation and sequencing strategies. The facility is managed by Dale Dorsett, Ph.D., who you can contact at 314-977-9218 or email@example.com, and Kathie Mihindukulasuriya, Ph.D., who you can contact at 314-977-9252 or firstname.lastname@example.org.
The Department of Biochemistry and Molecular Biology maintains a wide variety of computing resources. These range from network and backup services to state-of-the-art high-performance computing. The most recent addition to the department is the Gemini Computing Cluster that leverages modern technologies such as GPU computing capabilities. The cluster consists of 344 CPU cores, 80 GPUs and 1.3 TB of aggregate RAM, providing 135 TFLOPs peak computing power.
Other Facilities and Resources
Animal Care Facility
The 44,000-square-foot Animal Care Facility operated by SLU’s Department of Comparative Medicine has three full-time veterinarians and offers training, colony health surveillance and technical support, as well as consultation and collaborative services.
Animal Imaging Core Facility
The Department of Molecular Microbiology and Immunology’s Animal Imaging Core Facility offers non-invasive, small animal imaging using IVIS Spectrum instrument.
Flow Cytometry Research Core
SLU’s Flow Cytometry Research Core offers a FACS Callibur flow-cytometer with cell sorter, Biosciences LSR II, capable of 10-color analyses and Biosciences FACSAria, with simultaneous sorting of four populations. It has two full-time staff members and offers discounted rates to SLU researchers.
Lipidomics Core Facility
The Lipidomics Core Facility, operated by the department and the Center for Cardiovascular Research at Saint Louis University School of Medicine, is a University resource located in the Doisy Research Center. The facility focuses on small molecule identification and quantification by mass spectrometry.
Instrumentation in this core includes a Thermo Electron Surveyor LC and Quantum Ultra triple quadrupole electrospray ionization mass spectrometer, as well as two HP6890 gas chromatographs with FID detector and HP 5973 MS detector with both electron impact and chemical ionization sources.The facility is managed by Dave Ford, Ph.D. Contact him at 314-977-9264 or email@example.com.
The Saint Louis University Department of Chemistry houses an NMR facility, which is available to all researchers at SLU. The facility has a multinuclear Bruker spectrometer with the field strength of 16.4 Tesla, as well as a newly-installed Bruker Avance HDTM 700MHz NMR spectrometer. These instruments can be used to determine the structures of organic molecules and biomolecules, and can also be used in other dynamic studies.
The facility is located in Shannon Hall and is managed by the Department of Chemistry.
Research Microscopy and Histology Core
Offered by SLU’s Department of Pathology, the Research Microscopy and Histology Core provides a wide range of histological and microscopy services on a fee-for-service basis.