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Headshot of Daniela Salvemini wearing a white jacket

With $5.3 Million from NIH, DOD, Saint Louis University and University of Maryland Pain Researchers Set Their Sights on Migraine Relief

Thanks to $5.3 million from the Department of Defense (DOD) and the National Institutes of Health (NIH), Saint Louis University pain researcher Daniela Salvemini, Ph.D., and colleagues from the University of Maryland School of Dentistry (UMSOD) are in pursuit of a new way to treat migraine pain, a complex and painful disorder that affects over 30 million people in the U.S., including children as young as 5 years old.

The researchers will target two pain receptors in order to ‘switch off’ pain signals in the brain involved in inflammation.

Adding to researchers’ enthusiasm about this approach is a possible head start on the road to clinical trials: compounds that that target these pain receptors already exist, including one that is approved for the treatment of multiple sclerosis. As a part of this study, the team will be able to conduct pre-clinical screening, speeding the way to possible clinical trials repurposing these compounds for migraine pain. 

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Photo of Dr. Ajay Jain standing in his labratory

SLU Physician-Scientist Awarded $428,020 NIH Grant to Study Short Bowel Syndrome

A Saint Louis University School of Medicine physician-scientist has received funding from the National Institutes of Allergy and Infectious Diseases of the National Institutes of Health (NIH) to study Short Bowel syndrome (SBS).

Ajay Jain, M.D., professor of pediatrics, pharmacology, and physiology, received a highly coveted NIH R21 grant for $428,020. This round of funding compliments Jain’s recent NIH R01 grant for $1,893,750. With these two grants, Jain is focusing on comprehensively assessing gut-systemic signaling and the role of gut microbiota in preventing injury in SBS. 

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Photo of Dr. Adriana Montano standing in labratory

SLU’s Adriana Montaño Named to National Academy of Inventors for Rare Genetic Diseases Research

Researcher Adriana Montaño, Ph.D., professor of pediatrics, biochemistry and molecular biology at Saint Louis University School of Medicine, has been named a Senior Member of the National Academy of Inventors (NAI) for her internationally recognized work in the field of Lysosomal Storage Diseases (LSDs).

NAI Senior Members are active faculty, scientists, and administrators with success in patents, licensing, and commercialization and have produced technologies that have brought or aspire to bring a real impact on the welfare of society. 

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Meet a SLU Researcher: Richard J. DiPaolo, Ph.D.

Richard J. DiPaolo, Ph.D., is Professor and Interim Chair of the Dept. of Molecular Microbiology and Immunology, and he discusses how immunotherapies currently and in the future play a key role in combating human diseases.

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