Thursday, 07 January, 2021
Neuro@NoonByZoom, the interdisciplinary Neuroscience Journal Club at Saint Louis University will be held at noon on Jan. 7.
Dr. Gina Yosten will present a recent publication in Nature Neuroscience entitled “A prefrontal "paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice.” mice that were subjected to Juvenile Social Isolation (JSI) had reduces sociability when they became adults, as compared to adult mice that were Group-Housed (GH) throughout their lives.
Sociability was measured as an animal's responses during exposure to novel mice, as compared to exposure to novel objects. A neural correlate of such behavioral differences was observed in neural activity in the projection between the medial prefrontal cortex and the paraventricular nucleus of thalamus. This study demonstrates another circuit that is important to the complex processing of social networks, a locus that may be associated with psychiatric disorders.
Neuro@Noon is affiliated with the Henry and Amelia Nasrallah Center for Neuroscience.