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Department of Psychiatry & Behavioral Neuroscience Grand Rounds

Thursday, 10 November, 2022

NEWSLINK: Please publish

The Department of Psychiatry & Behavioral Neuroscience

will present a Grand Rounds from 12:00 PM to 1:00 PM


November 10, 2022


Common Adult Vaccinations and Incident Dementia

Jeffrey F. Scherrer, PhD.

Vice Chair for Research, Department of Family and Community Medicine

Professor Department of Family and Community Medicine and

Professor in the Department of Psychiatry and Behavioral Neuroscience

Executive Director of Research, AHEAD Institute

Saint Louis University School of Medicine

Harry S. Truman Memorial Veterans' Hospital, Research Service (WOC)

Editor-in-Chief, Family Practice 

Jeffrey Scherrer, P.h.D is Professor and Director of the Division of Research in the Department of Family and Community Medicine at Saint Louis University (SLU). Funded investigator since 2004 and a funded Principal Investigator for 15 years. His Research has focused on psychiatric and clinical epidemiology.  Scherrer’s first 10 years as a faculty member at Washington University School of Medicine, Department of Psychiatry, worked in twin studies and the etiology and patterns of comorbid psychiatric and substance use disorder, including alcohol misuse and use disorder, Since 2008 he has focused on funded research in clinical epidemiology. He has a track record of applying advanced methods to administrative medical record and medical claims data to a wide range of research questions and content areas. In his Veterans Health Administration (VA) Career Development Award, he used a large VA administrative medical record data base to study the relationship between depression, anxiety disorders and incident myocardial infarction. In VA and private sector cohorts, Scherrer then conducted numerous studies on prescription opioid pharmaco-epidemiology and the association between chronic opioid use and dose and new onset and worsening depression (R21MH101389). This retrospective cohort study has now been expanded to a prospective cohort of new opioid users to determine moderators of the association between chronic prescription opioid use and incident depression (R01DA043811). Dr. Scherrer completed a study of metformin and risk for dementia (R21AG055604) using big medical record data bases and he is finishing a Benter Foundation award to investigate potential protective effects of adult vaccinations on incident dementia in a VA cohort with replication in a MarketScan claims data base. He is concurrently studying the effects of PTSD, PTSD psychotherapy and poor health behaviors, incident cardiovascular and metabolic disease (R01HL125424) using VA administrative data. His productive application of big data research using medical records and medical claims across a variety of topics, including opioid pharmacoepidemiology, provides the evidence that he will succeed as a Principal Investigator for the current proposal.