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Thursday, 07 November, 2019

John Martin, Ph.D., director of the Center for Anatomical Science and Education, will present, “Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder,” for Neuro@Noon at noon on Thursday Nov. 7, in Room M260, Schwitalla Hall.

The paper describes behavioral, anatomical and electrophysiological findings and was published earlier this year in Neuron.  This article shows that treating mice that display autism with a bacteria Lactobacillus reuteri rescues the Autistic social deficits. An intact vagus nerve mediates this effect and it is also blocked by oxytocin inhibition. 

Neuro@Noon is the neuroscience journal club at Saint Louis University, affiliated with the Henry and Amelia Nasrallah Center for Neuroscience.