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John O'Leary to Keynote 2025 Cannonball Conference

09/12/2025

John O'Leary, a Saint Louis University alum (CSB '99), author, and motivational speaker, will deliver the keynote address at the 2025 Cannonball Conference. The conference is scheduled for Thursday, Oct. 23. 

In 1987, O'Leary was a curious nine-year old boy.  Playing with fire and gasoline, he created a massive explosion in his home and was burned on 100% of his body. He was given less than a 1% chance to live. 

John O'Leary poses for a photo on the SLU campus.

SLU alum John O’Leary (CSB ’99) will be the 2025 Cannonball Conference keynote speaker. Photo by Sarah Conroy

His epic story of survival was first showcased in “Overwhelming Odds,” the book his parents wrote in 2006.  It was this book that first invited O'Leary to embrace his miraculous recovery and share it with the world. Today, O'Leary inspires tens of thousands of people at more than 100 live and virtual events each year.  Consistently described as “the best speaker we've ever had,” his emotional storytelling, unexpected humor and authenticity make each presentation unforgettable. 

O'Leary is a two-time bestselling author of “On Fire:  The 7 Choices to Ignite a Radically Inspired Life” and “In Awe:  Rediscover Your Childlike Wonder to Unleash Inspiration, Meaning, and Joy.”  O'Leary's award-winning “Live Inspired” Podcast has more than seven million downloads and enjoys world-class guests such as Brene Brown, Mitch Albom, Jackie Joyner-Kersee and Bob Costas. 

A full-length feature film starring Joel Courtney, John Corbett, and William H. Macy based on his best-selling book is set to be released in theaters nationwide on October 10, 2025. Portions of “Soul on Fire” were filmed on SLU's campus in 2023. 

Regardless of his professional accomplishments, O'Leary considers his greatest success to be his marriage to his wife Beth, their four children and the relationships with his friends and family. 

O'Leary is excited to spend the day with staff. 

Registration for the 2025 Cannonball Conference will open on Wednesday, Sept. 17.