Researchers
Patrick Yeung Jr. and Daniela Salvemini.
Summary
This invention relates to compositions and methods for diagnosis and treatment of infertility, in particular endometriosis-related infertility. At present, the only way to diagnose endometriosis is by surgery, so there is generally a delay in treatment. The presence of sphingosine-1-phosphate receptor-1 (S1PR1) in the blood provides a biomarker for early detection of endometriosis. Treatment is provided by administering an agent that suppresses or blocks sphingosine-1-phosphate (S1P) or S1PR1 biological activity.
Intellectual Property Status
- U.S. patent pending