Department of Internal Medicine

The Department of Internal Medicine at the Saint Louis University School of Medicine offers state-of-the-art facilities, a faculty of outstanding clinical scholars and rapidly expanding research programs. Of equal importance, you will find a friendly, caring atmosphere and a love for learning that are part of the culture of this Jesuit University and medical center.

Ours is a well-established program with deep historical roots. In 1911, Charles Hugh Neilson, M.D., was appointed as the first director of the Department of Internal Medicine, marking the foundation of the department. The department celebrated its Centennial in 2011.

Our Divisions

Residency Training Programs

Explore our residency training program, as well as our subspecialty residency training programs, including:

Internal Medicine Research

From 2010 to 2015, 14 researchers in the Department of Internal Medicine have received funding from the National Institutes of Health (NIH), totaling $41,942,705. This funding has led to significant discoveries and inventions that have already had a major impact on the health of Americans.

Center for Vaccine Development

SLU's Center for Vaccine Development has played a key role in the development of vaccines that have saved lives and protected the public from important diseases, such as influenza, herpes virus infection and zika. It has also played a role in our national response to terrorism with its rapid testing of potential vaccines against smallpox.

Saint Louis University Liver Center

The Saint Louis University Liver Center is notable for its research on hepatitis C, with studies that have sought to understand the fundamentals mechanisms of how the hepatitis C virus attacks the liver and causes cirrhosis and liver cancer. Members of the Saint Louis University Liver Center have also been at the forefront of efforts to develop effective treatments for chronic hepatitis C, a battle that now seems largely won and may lead to the saving of hundreds of thousands of lives around the world.

Rheumatology Research

Researchers in the Division of Rheumatology have helped to develop effective treatments for systemic lupus erythematosus (SLE, or more simply Lupus), a disabling and often deadly autoimmune disease that disproportionately affects women and African Americans. We continue to obtain insights into how lupus is caused and how it damages target organs.

Research in Geriatric Medicine

Faculty in the Division of Geriatric Medicine have been national leaders in teaching people about aging successfully. They have studied and developed approaches to managing delirium, frailty and even Alzheimer’s Disease. Our researchers have pioneered the use of a unique mouse model, the SAMP8, to study mechanisms of Alzheimer’s and, more recently, to develop a novel therapeutic approach to this common disease of aging through the use of antisense RNA that blocks the conversion of amyloid precursor protein to beta amyloid.

Nephrology Research

Researchers in the Division of Nephrology have become national leaders in finding ways to increase the number of kidney transplants done each year, including the safe use of kidneys donated by liver donors. Our researchers have recently studied both the mechanism by which secondary hyperparathyroidism occurs in patients with chronic renal failure and the role of growth genes such as the SALL family in renal growth and development.